Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device

Description

This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow. Patients with an existing implanted shunt will wear the device to acquire longitudinal data.

Conditions

Hydrocephalus

Study Overview

Study Details

Study overview

This study evaluates the performance of a device for non-invasively assessing cerebrospinal fluid (CSF) shunt flow. Patients with an existing implanted shunt will wear the device to acquire longitudinal data.

Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device

Longitudinal Measurements of Flow in Cerebrospinal Fluid Shunts With a Wireless Thermal Anisotropy Measurement Device

Condition
Hydrocephalus
Intervention / Treatment

-

Contacts and Locations

Tampa

Tampa Marriott Water Street, Tampa, Florida, United States, 33602

Chicago

Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, United States, 60611

Chicago

MATTER, Chicago, Illinois, United States, 60611

Rolling Meadows

Northwest Special Recreation Association, Rolling Meadows, Illinois, United States, 60008

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. At least one existing ventricular CSF shunt (functional or non-functional, including "virtual off" and ligated, orphaned, abandoned, tied-off, or fractured distal catheters)
  • 2. Region(s) of intact skin overlying at least one unambiguously identifiable chronically indwelling ventricular shunt which crosses the clavicle and is appropriate in size for application of the study device
  • 3. Available for remote and in-person follow-up during the 30-day measurement period (for subjects using the study device at home)
  • 4. Subject is expected to remain in an inpatient setting for sufficient time to complete all required study device measurements (for subjects using the device in an inpatient hospital setting)
  • 5. Signed informed consent by subject or a parent, legal guardian, health care agent, or surrogate decision maker (according to local statutes)
  • 6. Subject or caregiver is able to clearly communicate and document information and shunt symptoms in English
  • 7. Verbal assent by minors 12 years of age and older who are able to understand the study and communicate their decision
  • 8. Patient is at least 5 years old but not more than 80 years old
  • 1. Presence of an interfering open wound or edema over any portion of the shunt
  • 2. Patient-reported history of adverse skin reactions to adhesives
  • 3. Investigator judges that the subject is likely to be lost to follow-up due to unavailability or clinical outcome being unobtainable
  • 4. Investigator judges that the subject is unlikely to successfully take reliable measurements at home (for subjects using the study device at home)
  • 5. Investigator judges that the subject/subject's caretaker would not be able to successfully place the device without assistance
  • 6. Use of the study device would interfere with standard patient care, or emergency surgery that cannot be delayed, or participation in the study will interfere with, or be detrimental to, administration of optimal healthcare to the subject
  • 7. Participation in any other investigational procedural, pharmaceutical, and/or device study that may influence the collection of valid data under this study

Ages Eligible for Study

5 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Rhaeos, Inc.,

Study Record Dates

2025-04