CONVIVO Endomicroscopy

Description

Visualization of the tissue microstructure during neurosurgery using a non destructive handheld imaging technology producing a real time digital image ("optical biopsy") at cellular resolution is a novel method that holds great promise for optimization and improvement of the surgical treatment of brain pathologies, brain tumors in particular. The goal of this project is to investigate and assess the ease of use of the CONVIVO FDA cleared system in discriminating healthy and abnormal tissues during in vivo use on the brain during neurosurgery in 30 patients with a working diagnosis of intrinsic brain tumors.

Conditions

Brain Tumor

Study Overview

Study Details

Study overview

Visualization of the tissue microstructure during neurosurgery using a non destructive handheld imaging technology producing a real time digital image ("optical biopsy") at cellular resolution is a novel method that holds great promise for optimization and improvement of the surgical treatment of brain pathologies, brain tumors in particular. The goal of this project is to investigate and assess the ease of use of the CONVIVO FDA cleared system in discriminating healthy and abnormal tissues during in vivo use on the brain during neurosurgery in 30 patients with a working diagnosis of intrinsic brain tumors.

A Feasibility Analysis of an in Vivo CONVIVO Endomicroscopy During Brain Surgery.

CONVIVO Endomicroscopy

Condition
Brain Tumor
Intervention / Treatment

-

Contacts and Locations

Manhasset

Northwell Health, Manhasset, New York, United States, 11030

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * . The patient is suffering from an intracranial lesion requiring surgery:
  • * Patients undergoing neurosurgical resection for intrinsic presumably high grade, invasive tumors.
  • * Patients undergoing neurosurgical resection for other brain tumors,.
  • * All patient groups will only be comprised of elective surgical patients who have signed the informed consent prior to use
  • * History of hypersensitivity to fluorescein
  • * History of allergy or bronchial asthma
  • * Renal failure - Children (patients less than 18 years of age)
  • * Pregnant women
  • * Breast feeding women
  • * Patients with inability to give informed consent

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Northwell Health,

Study Record Dates

2024-10-12