Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA

Description

Osteomyelitis is described as infection and inflammation of the long bone or bone marrow, often due to an open wound, operation, or invasive trauma.1 It is invasive and involves hematogenous seeding or contiguous spread of the infectious organism

Conditions

Osteomyelitis

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Study Overview

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Study Details

Study overview

Osteomyelitis is described as infection and inflammation of the long bone or bone marrow, often due to an open wound, operation, or invasive trauma.1 It is invasive and involves hematogenous seeding or contiguous spread of the infectious organism

Don't Treat Ghosts: Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA

Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSA

Condition
Osteomyelitis
Intervention / Treatment

-

Contacts and Locations

Dallas

Methodist Dallas Medical Center, Dallas, Texas, United States, 75203

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * • Admission to any MHS hospital between April 1, 2017 and April 1, 2023
  • * \> 18 years of age
  • * Documented osteomyelitis location of the lower limb via ICD-10 code
  • * Documented imaging of lower limb osteomyelitis during index admission
  • * Planned intravenous (IV) antibiotics for at least 4 weeks
  • * • IV antibiotics for less than 24 hours inpatient
  • * Planned surgical intervention documented at admission
  • * Patients receiving monotherapy with an anti-MRSA agent
  • * Positive MRSA culture during index admission
  • * Current outpatient antibiotic use on index admission
  • * Repeated hospital admission during study period

Ages Eligible for Study

18 Years to 75 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Methodist Health System,

Matthew Crotty, PharmD, PRINCIPAL_INVESTIGATOR, Methodist Dallas Medical Center

Study Record Dates

2024-06-23