Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Description

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency. The primary objective of this study is to determine the efficacy of amniotic membrane therapy in patients with interstitial cystitis/painful bladder syndrome (IC/PBS) as defined by clinically-significant improvement in validated symptom questionnaires.

Conditions

Interstitial Cystitis, Painful Bladder Syndrome, Painful Bladder Syndrome (PBS)

Study Overview

Study Details

Study overview

Interstitial cystitis/painful bladder syndrome (IC/PBS) is a clinical syndrome in which patients report symptoms of bladder and/or pelvic pain with pressure and/ or discomfort associated with urinary frequency and urgency. The primary objective of this study is to determine the efficacy of amniotic membrane therapy in patients with interstitial cystitis/painful bladder syndrome (IC/PBS) as defined by clinically-significant improvement in validated symptom questionnaires.

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome (IC/PBS): a Prospective, Double-Blind, Randomized Controlled Trial

Amniotic Membrane Therapy for Interstitial Cystitis/Painful Bladder Syndrome

Condition
Interstitial Cystitis
Intervention / Treatment

-

Contacts and Locations

Cleveland

University Hospitals, Cleveland, Ohio, United States, 44106

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients 18 years of age or older
  • * Female
  • * English Speaking
  • * Diagnosis of IC/PBS
  • * Have failed at least one prior treatment for IC/PBS
  • * Patients less than 18 years of age
  • * Unable to provide consent
  • * Non-English speaking
  • * Patients with known anatomical malformations of the ureters, bladder, or urethra

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

David Sheyn,

David Sheyn, MD, PRINCIPAL_INVESTIGATOR, University Hospitals Cleveland Medical Center

Study Record Dates

2026-06