RECRUITING

Upper and Lower Extremity Exercise and Exercise-Induced Hypoalgesia in Knee Osteoarthritis

Talk to us

Conditions

Knee OsteoarthritisKnee Pain ChronicCentral Pain Syndrome

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of the study is to explore the effects of arm exercise (UE, arm ergometer) vs. leg exercise (LE, cycling ergometer) on exercise-induced hypoalgesia (EIH), central pain mechanisms and knee pain in people with knee osteoarthritis (OA). Furthermore, we will explore relations of socioeconomic status, racial discrimination, acculturative stress, and autonomic function to exercise effects on EIH, central pain mechanisms, and knee pain. This will be a pilot randomized cross-over study where all participants undergo Day 1 (baseline assessments), Day 2 (UE or LE), and Day 3 (UE or LE).

Official Title

Comparing Effects of Upper Extremity Versus Lower Extremity Exercise on Exercise-Induced Hypoalgesia in People With Knee Osteoarthritis: A Pilot Cross-over Study

Quick Facts

Study Start:2023-11-15
Study Completion:2025-10-16
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06105788

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:45 Years to 90 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * age ≥45
  2. * activity-related knee pain
  3. * either no morning joint-related stiffness or stiffness that lasts ≤ 30 minutes.
  4. * knee pain at least 4 on a 0-10 pain scale
  5. * knee pain as a chief complaint if having multiple pain
  6. * understand English
  1. * peripheral neuropathy or other sensation loss on the body sites for pain measurements (i.e., the wrist, knee, the forearm)
  2. * use of medical devices electrically active (e.g., pacemaker)
  3. * chronic use of opioids
  4. * pregnant women
  5. * serious and uncontrolled concomitant disease, including cardiovascular, nervous system, pulmonary, renal, hepatic, metabolic, hormonal, endocrine, gastrointestinal or epileptic disease
  6. * rheumatoid arthritis, ankylosing spondylitis, and any neurological disorders that prevent the study procedure
  7. * cognitive impairment
  8. * history of a knee replacement surgery
  9. * inability to perform exercise due to severe pain or other symptoms
  10. * any intervention procedures for knee pain in the last 3 months

Contacts and Locations

Study Contact

Kosaku Aoyagi, PhD
CONTACT
9157478215
kaoyagi@utep.edu

Study Locations (Sites)

The University of Texas at El Paso
El Paso, Texas, 79968
United States

Collaborators and Investigators

Sponsor: University of Texas, El Paso

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-15
Study Completion Date2025-10-16

Study Record Updates

Study Start Date2023-11-15
Study Completion Date2025-10-16

Terms related to this study

Additional Relevant MeSH Terms

  • Knee Osteoarthritis
  • Knee Pain Chronic
  • Central Pain Syndrome