Study of DF6215 in Patients with Advanced Solid Tumors

Description

A Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in Combination Therapy in Patients with Advanced (Unresectable, Recurrent, or Metastatic) Solid Tumors; is designed to assess the safety, tolerability, and preliminary efficacy of DF6215 alone or in combination with pembrolizumab in patients with advanced solid tumors. The study is open-label, meaning both participants and investigators are aware of the treatment being administered.

Conditions

Solid Tumor, Adult, Solid Tumor Cancer

Study Overview

Study Details

Study overview

A Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in Combination Therapy in Patients with Advanced (Unresectable, Recurrent, or Metastatic) Solid Tumors; is designed to assess the safety, tolerability, and preliminary efficacy of DF6215 alone or in combination with pembrolizumab in patients with advanced solid tumors. The study is open-label, meaning both participants and investigators are aware of the treatment being administered.

A Phase I/Ib, First-In-Human, Multi-Part, Open-Label Study to Investigate the Safety, Tolerability, Pharmacokinetics, Biological and Clinical Activity of DF6215 Monotherapy and in Combination Therapy in Patients with Advanced (Unresectable, Recurrent, or Metastatic) Solid Tumors

Study of DF6215 in Patients with Advanced Solid Tumors

Condition
Solid Tumor, Adult
Intervention / Treatment

-

Contacts and Locations

Los Angeles

The Angeles Clinic and Research Institute - West Los Angeles Office, Los Angeles, California, United States, 90025

Orange

University of California Irvine Medical Center, Orange, California, United States, 92868

San Diego

University of California San Diego Moores Cancer Center, San Diego, California, United States, 92093

Santa Monica

Sarcoma Oncology Center, Santa Monica, California, United States, 90403

Tampa

Tampa General Hospital, Tampa, Florida, United States, 33606

Tampa

Moffitt Cancer Center, Tampa, Florida, United States, 33612

New York

NYU Langone Health, New York, New York, United States, 10016

Providence

Lifespan - Rhode Island Hospital, Providence, Rhode Island, United States, 02903

Nashville

SCRI Oncology Partners, Nashville, Tennessee, United States, 37203

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

    Ages Eligible for Study

    18 Years to

    Sexes Eligible for Study

    ALL

    Accepts Healthy Volunteers

    No

    Collaborators and Investigators

    Dragonfly Therapeutics,

    Study Record Dates

    2027-12