Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

Description

This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed recovery. This project aims to better identify biomarkers for diagnosis and prognosis and maximize recovery from mTBI.

Conditions

Brain Concussion, Mild Traumatic Brain Injury, Headache, Post-Concussion Symptoms

Study Overview

Study Details

Study overview

This study aims to examine the long-term effect of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, on chronic headaches following mild traumatic brain injury (mTBI). rTMS has been shown to be effective in reducing chronic headaches without side effects commonly seen in medications, such as sleepiness and addiction. This study uses rTMS to manage chronic headaches to improve post-concussion symptoms and reduce the economic burden due to delayed recovery. This project aims to better identify biomarkers for diagnosis and prognosis and maximize recovery from mTBI.

Using Repetitive Transcranial Magnetic Stimulation to Manage Headaches and Improve Rehabilitation Outcomes in Mild Traumatic Brain Injury: A Longitudinal Study

Repetitive Transcranial Magnetic Stimulation for Post-concussion Headaches

Condition
Brain Concussion
Intervention / Treatment

-

Contacts and Locations

Syracuse

SUNY Upstate Medical University, Syracuse, New York, United States, 13210

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 18 - 55 years old who were actively working prior to mTBI
  • * mTBI with loss of consciousness for less than 30 min, initial Glasgow Coma Scale between 13 and 15, or post-traumatic amnesia for ≤ 24 hours
  • * diagnosis of persistent post-traumatic headache according to the International Classification of Headache Disorders, 3rd edition (ICHD-3) criteria
  • * headache develops within 7 days after head trauma
  • * headache persists for \>=3 months after head trauma despite receiving standard care
  • * average persistent headache intensity is \>= 3/10 of the numerical rating scale (NRS) on \>=3days/week
  • * no evidence of radiculopathy or peripheral neuropathy on electromyography or clinical evaluation
  • * no evidence of other possible causes of headaches
  • * history of chronic headache diagnoses such as migraine, tension, or cluster headaches prior to the incidence of mTBI
  • * history of other neurologic conditions with medications affecting the central nervous system
  • * contraindications of receiving TMS (e.g., a history of epileptic seizure and having implants like a cardiac pacemaker or intracerebral vascular clip

Ages Eligible for Study

18 Years to 55 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

State University of New York - Upstate Medical University,

Yi-Ling Kuo, PT, PhD, PRINCIPAL_INVESTIGATOR, State University of New York - Upstate Medical University

Study Record Dates

2027-10-23