Ketogenic Diet and Diabetes Demonstration Project

Description

KDDP is a prospective, 12-month pilot study comparing the effects of a novel lifestyle program, the Ketogenic Diet and Diabetes Demonstration Project (KDDP) to those of the National Diabetes Prevention Program (NDDP). KDDP is modeled to mimic the delivery platform of NDPP with the exception that participants in KDDP will be placed on a medically-supervised ketogenic diet, and participants in NDPP will be placed on a low fat diet. The purpose of this study is to compare the metabolic effects of the KDDP and the NDPP on glycemic control, lipid parameters, blood pressure, heart rate, weight, and coronary artery calcium scores in individuals with either type 2 diabetes or prediabetes.

Conditions

Type 2 Diabetes, PreDiabetes, Obesity, Ketogenic Dieting

Study Overview

Study Details

Study overview

KDDP is a prospective, 12-month pilot study comparing the effects of a novel lifestyle program, the Ketogenic Diet and Diabetes Demonstration Project (KDDP) to those of the National Diabetes Prevention Program (NDDP). KDDP is modeled to mimic the delivery platform of NDPP with the exception that participants in KDDP will be placed on a medically-supervised ketogenic diet, and participants in NDPP will be placed on a low fat diet. The purpose of this study is to compare the metabolic effects of the KDDP and the NDPP on glycemic control, lipid parameters, blood pressure, heart rate, weight, and coronary artery calcium scores in individuals with either type 2 diabetes or prediabetes.

Ketogenic Diet and Diabetes Demonstration Project

Ketogenic Diet and Diabetes Demonstration Project

Condition
Type 2 Diabetes
Intervention / Treatment

-

Contacts and Locations

Albuquerque

University of New Mexico, Albuquerque, New Mexico, United States, 87131

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Men and women ≥ 18 years old
  • * BMI ≥27 kg/m2
  • * Hemoglobin A1c ≥ 5.7% and/or fasting plasma glucose of 100-125 mg/dL
  • * Known clinical cardiovascular disease (i.e. prior stroke, myocardial infarction, peripheral artery disease)
  • * LDL cholesterol ≥ 190 mg/dL
  • * Triglycerides ≥ 500 mg/dL
  • * History of type 1 diabetes
  • * History of diabetic ketoacidosis
  • * Individuals requiring insulin
  • * Advanced renal disease
  • * Advanced liver disease
  • * Terminal cancer
  • * Pregnancy

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of New Mexico,

Kristen Gonzales, MD, PRINCIPAL_INVESTIGATOR, University of New Mexico

Study Record Dates

2025-10-01