Sing For Your Saunter Part 2 R33

Description

The goal of this clinical trial is to compare to rhythm-based walking interventions to enhance gait in people with Parkinson's disease. The main questions it aims to answer are: * How does rhythm-based training influence walking performance? * How does brain activity change following rhythm-based training? Participants will perform walking to music and walking while singing, and will train on the use of these rhythms for 12 weeks. The investigators will compare the effects of training with music to training with singing.

Conditions

Parkinson Disease

Study Overview

Study Details

Study overview

The goal of this clinical trial is to compare to rhythm-based walking interventions to enhance gait in people with Parkinson's disease. The main questions it aims to answer are: * How does rhythm-based training influence walking performance? * How does brain activity change following rhythm-based training? Participants will perform walking to music and walking while singing, and will train on the use of these rhythms for 12 weeks. The investigators will compare the effects of training with music to training with singing.

Sing for Your Saunter: Using Self-Generated Rhythmic Cues to Enhance Gait in Parkinson's

Sing For Your Saunter Part 2 R33

Condition
Parkinson Disease
Intervention / Treatment

-

Contacts and Locations

Saint Louis

Washington University School of Medicine, Saint Louis, Missouri, United States, 63108

Saint Louis

Washington University School of Medicine, Saint Louis, Missouri, United States, 63108

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • 1. at least 30 years of age
  • 2. diagnosis of idiopathic, typical Parkinson disease according to the UK Brain Bank Criteria
  • 3. Hoehn \& Yahr stages 2-3 (mild to moderate disease severity)
  • 4. evidence of walking impairment (score at least 1 on gait item of MDS_UPDRS)
  • 1. diagnosis of any other neurological condition
  • 2. a score of 2 or greater on item # 3 on the freezing of gait questionnaire
  • 3. significant cognitive impairment
  • 4. unstable medical or concomitant illnesses or psychiatric conditions which, in the opinion of the investigators, would preclude successful participation
  • 5. cardiac problems that interfere with ability to safely participate
  • 6. orthopedic problems in the lower extremities or spine that may limit walking
  • 7. contraindications for magnetic resonance imaging
  • 8. unable to walk for 10 continuous minutes independently
  • 9. left-handed
  • 10. uncontrolled tremor or dyskinesia

Ages Eligible for Study

30 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Washington University School of Medicine,

Study Record Dates

2025-11-30