RECRUITING

Immune Profiling for Cancer Immunotherapy Response

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

In patients clinically treated with FDA-approved immunotherapy the investigators will assess the predictive value of pre- and on-treatment 1) immune-methylation profiling across cancer types, and 2) immune-methylation profiling and cytokine profiling within cancer types.

Official Title

Immune Profiling for Cancer Immunotherapy Response

Quick Facts

Study Start:2022-10-03
Study Completion:2026-01-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06116032

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Cancer patients receiving or will receive immunotherapy under FDA- approved indication (e.g. checkpoint inhibitor therapy with pembrolizumab, nivolumab, or ipilimumab, or cellular immunotherapy).
  2. * Participants are eligible regardless of the type of prior therapy (i.e. prior immunotherapy treated participants can be included).
  1. * Pregnant women/fetuses/neonates
  2. * Prisoners
  3. * Decision-impaired individuals

Contacts and Locations

Study Contact

Brock C Christensen, PhD
CONTACT
603-650-1827
brock.c.christensen@dartmouth.edu
Hannah G Stolrow, BA
CONTACT
7205174950
hannah.stolrow@dartmouth.edu

Principal Investigator

Brock C Christensen, PhD
PRINCIPAL_INVESTIGATOR
Dartmouth College

Study Locations (Sites)

Dartmouth-Hitchcock Medical Center
Lebanon, New Hampshire, 03756
United States

Collaborators and Investigators

Sponsor: Dartmouth-Hitchcock Medical Center

  • Brock C Christensen, PhD, PRINCIPAL_INVESTIGATOR, Dartmouth College

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-10-03
Study Completion Date2026-01-01

Study Record Updates

Study Start Date2022-10-03
Study Completion Date2026-01-01

Terms related to this study

Keywords Provided by Researchers

  • Immunotherapy

Additional Relevant MeSH Terms

  • Cancer
  • Tumor, Solid
  • Hematologic Malignancy
  • Blood Cancer