Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.
For general information about clinical research, read Learn About Studies.
Eligibility Criteria
- * LDL-C ≥115 mg/dL and ≤190 mg/L
- * BMI of 25-35 kg/m2
- * Intake of \<14 eggs/week for the prior 3 months
- * Blood pressure \<140/90 mmHg
- * Fasting blood glucose \<126 mg/dL
- * Fasting triglycerides \<350 mg/dL
- * ≤10% change in body weight in the prior 6 months
- * Type 1 or type 2 diabetes or fasting blood glucose ≥126 mg/dL
- * Prescription of anti-hypertensive, lipid lowering or glucose lowering drugs
- * Intake of supplements that affect the outcomes of interest and unwilling to cease during the study period
- * Diagnosed liver, kidney, or autoimmune disease
- * Prior cardiovascular event (e.g., stroke, heart attack)
- * Current pregnancy or intention of pregnancy within the next 6 months
- * Lactation within prior 6 months
- * Follows a vegetarian or vegan diet
- * Food allergies/intolerance/sensitives/dislikes of foods included in the study menu
- * Antibiotic use within the prior 1 month
- * Oral steroid use within the prior 1 month
- * Use of tobacco or nicotine containing products with in the past 6 months
- * Cancer any site within the past 10 years (eligible if ≥10 years without recurrence) or non-melanoma skin cancer with in the past 5 years (eligible if ≥5 years without recurrence)
- * Participation in another clinical trial within 30 days of baseline
- * Currently following a restricted or weight loss diet
- * Prior bariatric surgery
- * Intake of \>14 alcoholic drinks/week and/or lack of willingness to consume a maximum of two standard drinks per week while enrolled in the study and/or not willing to avoid alcohol consumption for 48 hour prior to test visits
Ages Eligible for Study
30 Years to 60 Years
Sexes Eligible for Study
ALL
Accepts Healthy Volunteers
Yes