Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

Description

The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.

Conditions

Exercise Training, Aging

Study Overview

Study Details

Study overview

The goal of this behavioral clinical trial is to learn how to increase physical activity in mid-life adults. Specifically, can guided imagery that includes creating mental pictures increase excitement about working out. Participants will be asked to complete testing at the beginning of the study, following 6-weeks of an in-person exercise program, and 6-weeks after finishing the exercise program. Testing will include an exercise test, MRI, questionnaires, computer tasks, and a blood draw.

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging Among Mid-Life Adults: Phase II

Guided Episodic Future Thinking to Increase Physical Activity Adherence and Promote Healthy Brain Aging

Condition
Exercise Training
Intervention / Treatment

-

Contacts and Locations

Kansas City

University of Kansas Medical Center, Kansas City, Kansas, United States, 66160

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * speak English
  • * have access to reliable communication (a telephone or cell phone, computer, etc.)
  • * normal or corrected to normal vision and hearing
  • * ambulatory (without the use of assistive devices)
  • * physically underactive
  • * able to give informed consent
  • * able to exercise continuously on the recumbent stepper exercise device for 4 minutes greater than or equal to 25 watts to demonstrate ability to perform exercise on stepper \& no aerobic exercise contraindications or other safety/physical concerns
  • * able to communicate with investigators, follow 2-step command \& correctly answer consent comprehension questions
  • * stable blood pressure and statin medication doses for 30 days as these affect vascular health/hemodynamics
  • * willing and able to safely enter magnetic resonance (MR) scanner and attempt the MR scan
  • * willing and able to attempt a blood draw
  • * patients with arrhythmias or acute cardiac events will be excluded due to potential complications with the supervised moderate exercise
  • * at risk for hazard due to magnetic fields due to MR safety concerns
  • * have any neurologic or psychiatric disorder except depression, anxiety (including post-traumatic stress disorder)
  • * have history of seizures or head trauma due to MR data quality

Ages Eligible for Study

45 Years to 65 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Kansas Medical Center,

Laura Martin, PRINCIPAL_INVESTIGATOR, University of Kansas Medical Center

Study Record Dates

2027-05