RECRUITING

ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

While there has been a significant increase in the uptake of antiretroviral therapy among women living with HIV (WLHIV) in many low- and-middle income countries (LMICs), the coverage of cervical cancer screening and treatment (CCST) among WLHIV remains low. This study aims to leverage the available infrastructure for HIV care and treatment programs in Nigeria to integrate cervical cancer screening and treatment and conduct a cluster randomized, hybrid type III trial design to assess the comparative effectiveness of a Core set of implementation strategies versus a Core+ (enhanced) set of implementation strategies to implement cervical cancer screening, onsite treatment, referral and referral completion, treatment, and retention in care among WLHIV. The overarching goal is to improve the health and life expectancy of WLHIV with co-occurring cervical cancer.

Official Title

ACCESS: Accelerating Cervical Cancer Elimination Through the Integration of Screen-and-treat Services

Quick Facts

Study Start:2023-11-13
Study Completion:2027-08-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06128304

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:25 Years to 65 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Women living with HIV
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Gregory Aarons, PhD
CONTACT
858-966-7703
gaarons@health.ucsd.edu
Echezona Ezeanolue, MD, MPH
CONTACT
+234 803 773 9972
echezona.ezeanolue@unn.edu.ng

Principal Investigator

Gregory Aarons, PhD
PRINCIPAL_INVESTIGATOR
University of California, San Diego

Study Locations (Sites)

UC San Diego
La Jolla, California, 92093
United States

Collaborators and Investigators

Sponsor: University of California, San Diego

  • Gregory Aarons, PhD, PRINCIPAL_INVESTIGATOR, University of California, San Diego

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-11-13
Study Completion Date2027-08-31

Study Record Updates

Study Start Date2023-11-13
Study Completion Date2027-08-31

Terms related to this study

Keywords Provided by Researchers

  • Implementation Science
  • Cluster randomized trial
  • Capacity building
  • Low and middle income countries
  • Research infrastructure
  • Exploration Preparation Implementation Sustainment (EPIS)
  • EPIS Framework

Additional Relevant MeSH Terms

  • HIV
  • Cervical Cancer