COMPLETED

Comparison of Procedural Sedation in TEE

Conditions

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The objective of this proposal is to conduct a prospective randomized study comparing the utility of sedating patients undergoing transesophageal echocardiographic studies with a novel, recently-FDA-approved sedative agent, remimazolam, versus the sedative used in our current practice at UAB, propofol. This study will investigate whether remimazolam offers any benefit over current care vis-à-vis hemodynamics or efficiency/throughput. This study will be conducted at the University of Alabama at Birmingham. All outpatients and inpatients scheduled for elective/non-emergent TEE in the UAB Heart and Vascular Center TEE lab will be considered for enrollment.

Official Title

Comparison of Remimazolam With Propofol for Procedural Sedation in TEE

Quick Facts

Study Start:2025-02-25
Study Completion:2025-12-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06129188

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 89 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Inpatients and outpatients \>=18 years who are scheduled to undergo elective/non-emergent transesophageal echocardiography at the UAB Heart and Vascular Center TEE Lab.
  1. * Patients undergoing emergent TEE procedure in the HVC TEE Lab.
  2. * Patients undergoing elective or emergent TEE procedure in the ICU and/or at the patient bedside.
  3. * Patients undergoing elective or emergent TEE procedure in a location other than HVC TEE Lab.
  4. * Patients undergoing an additional procedure or surgery (before or after TEE) as part of the same anesthetic, except for DC Cardioversion.
  5. * Children under the age of 19 years (or under 50 kg body weight if age is unknown).
  6. * Pregnant patients.
  7. * Breastfeeding/nursing patients.
  8. * Incarcerated patients.
  9. * Patients enrolled in a concurrent ongoing interventional randomized clinical trial.

Contacts and Locations

Study Locations (Sites)

University of Alabama at Birmingham Hospital
Birmingham, Alabama, 35233
United States

Collaborators and Investigators

Sponsor: University of Alabama at Birmingham

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-02-25
Study Completion Date2025-12-01

Study Record Updates

Study Start Date2025-02-25
Study Completion Date2025-12-01

Terms related to this study

Additional Relevant MeSH Terms

  • Anesthesia