COMPLETED

Cognitive Rehabilitation in Post-COVID-19 Syndrome

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.

Official Title

Cognitive Strategy Training in Post-COVID-19 Syndrome: A Feasibility Trial

Quick Facts

Study Start:2024-01-29
Study Completion:2025-06-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06136871

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 60 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT
Inclusion CriteriaExclusion Criteria
  1. * self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score \>43)
  2. * self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
  3. * documented prior diagnosis of COVID-19
  4. * read, write, and speak English fluently
  5. * ability to provide valid informed electronic consent
  1. * diagnosis of severe neurological or psychiatric condition(s)
  2. * dementia symptoms as indicated by a score of \<23 on the Montreal Cognitive Assessment (MoCA)
  3. * untreated sleep apnea (≥5 on the STOPBANG)
  4. * prior cancer treatment
  5. * severe depressive symptoms (\>21 on the Patient Health Questionnaire-9)

Contacts and Locations

Principal Investigator

Anna E Boone, PhD, OTR/L
PRINCIPAL_INVESTIGATOR
University of Missouri Occupational Therapy

Study Locations (Sites)

University of Missouri Department of Occupational Therapy
Columbia, Missouri, 65211
United States

Collaborators and Investigators

Sponsor: University of Missouri-Columbia

  • Anna E Boone, PhD, OTR/L, PRINCIPAL_INVESTIGATOR, University of Missouri Occupational Therapy

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-01-29
Study Completion Date2025-06-30

Study Record Updates

Study Start Date2024-01-29
Study Completion Date2025-06-30

Terms related to this study

Keywords Provided by Researchers

  • covid-19
  • metacognition
  • cognition
  • telehealth
  • activities of daily living

Additional Relevant MeSH Terms

  • Post-COVID-19 Syndrome