Cognitive Rehabilitation in Post-COVID-19 Syndrome

Description

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.

Conditions

Post-COVID-19 Syndrome

Study Overview

Study Details

Study overview

The first aim of this study is to determine the feasibility of delivering CO-OP remotely to individuals experiencing cognitive impairments that limit everyday activities in post-COVID-19 syndrome (PCS). The second aim of this study is to assess the effect of CO-OP on activity performance, subjective and objective cognition, and quality of life in a sample of individuals with PCS. The research team hypothesizes that effect size estimations will indicate that CO-OP will have a greater positive effect, compared to an inactive control group, on activity performance, subjective and objective cognition, and quality of life in a sample of individuals who self-report PCS and cognitive impairment.

Cognitive Strategy Training in Post-COVID-19 Syndrome: a Feasibility Trial

Cognitive Rehabilitation in Post-COVID-19 Syndrome

Condition
Post-COVID-19 Syndrome
Intervention / Treatment

-

Contacts and Locations

Columbia

University of Missouri Department of Occupational Therapy, Columbia, Missouri, United States, 65211

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * self-reported cognitive symptoms persisting for at least 6 weeks following COVID-19 infection (Cognitive Failures Questionnaire (CFQ) score \>43)
  • * self-identified activity performance goals per the Canadian Occupational Performance Measure (COPM)
  • * documented prior diagnosis of COVID-19
  • * read, write, and speak English fluently
  • * ability to provide valid informed electronic consent
  • * diagnosis of severe neurological or psychiatric condition(s)
  • * dementia symptoms as indicated by a score of \<23 on the Montreal Cognitive Assessment (MoCA)
  • * untreated sleep apnea (≥5 on the STOPBANG)
  • * prior cancer treatment
  • * severe depressive symptoms (\>21 on the Patient Health Questionnaire-9)

Ages Eligible for Study

18 Years to 60 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Missouri-Columbia,

Anna E Boone, PhD, OTR/L, PRINCIPAL_INVESTIGATOR, University of Missouri Occupational Therapy

Study Record Dates

2025-02