Optimize Pediatric OCT Imaging

Description

Handheld optical coherence tomography (OCT) has become an important imaging modality to evaluate the pediatric retina. The objective of this pilot study is to compare a new contact OCT system (Theia Imaging) with an investigational noncontact OCT system (Duke Biomedical Engineering) to assess their ability to image the pediatric retina. The investigators hypothesize that the contact OCT system is superior in imaging larger areas of the retina (larger field-of-view), while it has similar resolution to image the retina substructures (non-inferior image quality).

Conditions

Retinal Disease, Glaucoma, Optic Nerve Diseases

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Study Overview

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Study Details

Study overview

Handheld optical coherence tomography (OCT) has become an important imaging modality to evaluate the pediatric retina. The objective of this pilot study is to compare a new contact OCT system (Theia Imaging) with an investigational noncontact OCT system (Duke Biomedical Engineering) to assess their ability to image the pediatric retina. The investigators hypothesize that the contact OCT system is superior in imaging larger areas of the retina (larger field-of-view), while it has similar resolution to image the retina substructures (non-inferior image quality).

Optimize Pediatric OCT (Optical Coherence Tomography) Imaging: a Pilot Study

Optimize Pediatric OCT Imaging

Condition
Retinal Disease
Intervention / Treatment

-

Contacts and Locations

Durham

Duke University Eye Center, Durham, North Carolina, United States, 27710

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Group 1 - Healthy adult volunteers
  • * Subject is able and willing to consent to study participation
  • * Subject is more than 18 years of age
  • * Healthy adult volunteers without known ocular issues other than refractive error
  • * Pregnancy Reasonably Excluded Guide (PREG) evaluation on women of childbearing potential
  • * Group 2 - Pediatric participants
  • * Health care provider, knowledgeable of protocol, agrees that study personnel could contact the parent/legal guardian
  • * Parent/legal guardian is able and willing to consent to study participation
  • * Pediatric patient less than 18 years of age in Duke Eye Center ophthalmology clinics or undergoing clinically-indicated examination under anesthesia at Duke Eye Center
  • * Group 1 - Healthy adult volunteers
  • * Students or employees under direct supervision of the investigators
  • * Subjects with prior problems with pupil dilation
  • * Pregnant woman if receiving dilating drops
  • * Group 2 - Pediatric participants
  • * Parent/legal guardian unwilling or unable to provide consent
  • * Participant has a health or eye condition that preclude eye examination or retinal imaging (such as corneal opacity or cataract)

Ages Eligible for Study

to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Duke University,

Study Record Dates

2025-12