Sleep Length and Euploid Embryo Transfer Prospective Study

Description

Sleep is a critical component of daily life that significantly influences health and well-being. Despite the integral role sleep plays in life, its effect on women's reproductive health, and its subsequent impact on fertility, is largely understudied. The purpose of the SLEEP Study is to investigate the link between sleep and fertility. Participants will use a wireless wearable device mounted on the finger to measure sleep in the weeks preceding and following an embryo transfer during treatment with in vitro fertilization. The investigators hope that these findings will inform future therapies that improve sleep and fertility outcomes.

Conditions

Infertility, Female

Study Overview

Study Details

Study overview

Sleep is a critical component of daily life that significantly influences health and well-being. Despite the integral role sleep plays in life, its effect on women's reproductive health, and its subsequent impact on fertility, is largely understudied. The purpose of the SLEEP Study is to investigate the link between sleep and fertility. Participants will use a wireless wearable device mounted on the finger to measure sleep in the weeks preceding and following an embryo transfer during treatment with in vitro fertilization. The investigators hope that these findings will inform future therapies that improve sleep and fertility outcomes.

Sleep Length and Euploid Embryo Transfer Prospective Study

Sleep Length and Euploid Embryo Transfer Prospective Study

Condition
Infertility, Female
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern Memorial Hospital, Chicago, Illinois, United States, 60611

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Undergoing a single euploid frozen embryo transfer
  • * Patient's 1st, 2nd, or 3rd embryo transfer (prior fresh or frozen transfers included)
  • * Primary infertility diagnosis of polycystic ovary syndrome
  • * BMI \> 40
  • * Diagnosis of primary ovarian insufficiency (FSH \> 40)
  • * Night work
  • * High risk of poor outcomes of fertility treatment \[\> 2 prior miscarriages (women with recurrent pregnancy loss), significant uterine factor infertility \[\>/= 2 myomectomies (open abdominal or laparoscopic) or any non-hystoeroscopic myomectomy entering the endometrial cavity\]
  • * Undergoing medical fertility preservation for a significant medical co-morbidity
  • * Current cancer diagnosis
  • * \> 3 prior failed embryo transfers in attempt for current live birth

Ages Eligible for Study

18 Years to 45 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Northwestern University,

Jessica Walter, MD, MSCE, PRINCIPAL_INVESTIGATOR, Northwestern University

Study Record Dates

2025-07-31