RECRUITING

A Digital Smoking Cessation Intervention for Helping American Indians and Alaska Natives Quit Smoking

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This clinical trial compares a new smoking cessation smartphone application (app) (iCanQuit) to an existing smarphone app (National Cancer Institute \[NCI\] QuitGuide) for helping American Indians and Alaska Natives (AIANs) quit smoking. Compared to other racial/ethnic groups, AIANs have 6 times higher rates of developing smoking-related cancers, including lung cancer. Commercial cigarette smoking accounts for half of all deaths among AIANs nationwide. AIANs' often lack of access to smoking cessation interventions, which may be due to inequities in the healthcare system, lack of health insurance, living in rural areas, systemic racism, and historical trauma. There is also a lack of effective smoking cessation interventions for AIANs. Smartphone apps have the potential to deliver a low-cost smoking cessation intervention with wide reach to AIANs. Apps require no in-person delivery and no provider training, do not require integration into complex hospital systems, can be freely accessed on an app store, and are available at any time and any place. iCanQuit is a behavioral intervention designed to help adults stop smoking by teaching skills for coping with smoking urges, staying motivated, and preventing relapse. The iCanQuit app intervention may be more effective than the currently available NCI QuitGuide app at helping AIANs quit smoking.

Official Title

Digital Smoking Cessation Intervention for Nationally-Recruited American Indians and Alaska Natives: A Full-Scale Randomized Controlled Trial

Quick Facts

Study Start:2025-07-03

Study Completion:2028-11-30

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06145763

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:Yes

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Self-identify as American Indian or Alaska Native, either alone or in combination with other races * Age 18 and older * Has smoked daily for the past year * Interest in quitting smoking within the next 30 days * Willing to be randomly assigned to either app * Have daily access to their own Android or iPhone * Able to download a smartphone app * Be willing and able to read English * Not currently or within past 30 days using other smoking cessation behavioral interventions or smoking cessation pharmacotherapies * Have never participated in our prior research * Have no other household or family member participating * Being willing to complete the 3, 6, and 12-month follow-up assessments * Providing email, phone number(s), and mailing address * Living off United States (US) AIAN tribal reservations or living on five Northern Plains tribal reservations from whom we would obtain approvals to recruit	* Currently (i.e., within past 30 days) using other smoking cessation behavioral interventions * Has participated in our prior research trials * Has used the National Cancer Institute's (NCI's) QuitGuide app * Not willing to complete a follow-up survey at 3, 6, and 12 months post-randomization * Not providing email, phone number(s), and mailing address

Inclusion Criteria

Exclusion Criteria

* Self-identify as American Indian or Alaska Native, either alone or in combination with other races
* Age 18 and older
* Has smoked daily for the past year
* Interest in quitting smoking within the next 30 days
* Willing to be randomly assigned to either app
* Have daily access to their own Android or iPhone
* Able to download a smartphone app
* Be willing and able to read English
* Not currently or within past 30 days using other smoking cessation behavioral interventions or smoking cessation pharmacotherapies
* Have never participated in our prior research
* Have no other household or family member participating
* Being willing to complete the 3, 6, and 12-month follow-up assessments
* Providing email, phone number(s), and mailing address
* Living off United States (US) AIAN tribal reservations or living on five Northern Plains tribal reservations from whom we would obtain approvals to recruit

* Currently (i.e., within past 30 days) using other smoking cessation behavioral interventions
* Has participated in our prior research trials
* Has used the National Cancer Institute's (NCI's) QuitGuide app
* Not willing to complete a follow-up survey at 3, 6, and 12 months post-randomization
* Not providing email, phone number(s), and mailing address

Contacts and Locations

Study Contact

Brie Sullivan

CONTACT

206-667-5238

bsulliva@fredhutch.org

Principal Investigator

Jonathan B. Bricker

PRINCIPAL_INVESTIGATOR

Fred Hutch/University of Washington Cancer Consortium

Study Locations (Sites)

Fred Hutch/University of Washington Cancer Consortium

Seattle, Washington, 98109

United States

Collaborators and Investigators

Sponsor: Fred Hutchinson Cancer Center

Jonathan B. Bricker, PRINCIPAL_INVESTIGATOR, Fred Hutch/University of Washington Cancer Consortium

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-07-03

Study Completion Date2028-11-30

Study Record Updates

Study Start Date2025-07-03

Study Completion Date2028-11-30

Terms related to this study

Additional Relevant MeSH Terms

Cigarette Smoking-Related Carcinoma