RECRUITING

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The study will compare the effectiveness of two relatively brief and scalable evidence-based interventions: the Stanley Brown Safety Planning Intervention and Follow-up Contacts (SPI+), a suicide-specific intervention that helps people prevent suicidal crises from escalating, and Interpersonal Psychotherapy for Adolescents Ultra Short Crisis Intervention (IPT-A SCI), a psychotherapeutic crisis intervention treatment for suicidal adolescents that teaches youth skills to prevent suicidal crises and addresses interpersonal problems that lead to suicidal crises. The results will inform the future standard of care for youth at risk for suicide presenting in the ED setting. This project focuses on suicidal youth ages 12-19 in three ethnically and racially diverse urban areas: Philadelphia, Pennsylvania; Baltimore, Maryland; and upper Manhattan/lower Bronx in New York City.

Official Title

Preventing Suicidal Behavior With Diverse High-Risk Youth in Acute Care Settings

Quick Facts

Study Start:2025-03-10
Study Completion:2028-10-14
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06151158

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:12 Years to 19 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:CHILD, ADULT
Inclusion CriteriaExclusion Criteria
  1. * Acute care visit for suicide-related concern or screen positive on a suicide risk screener (serious SI as indicated by a C-SSRS screening endorsing question two "Have you actually had any thoughts of killing yourself?" in past four weeks or SA in past four weeks);
  2. * Has a cell phone with ability to receive phone calls and text messages over the 12-month follow-up;
  3. * Ability to speak, understand, and read in English or Spanish
  1. * Significant cognitive or developmental delays that prevent understanding or using SPI or IPT-A SCI. Participants must be verbally fluent and have the ability to communicate verbally. This will, in part, be determined by notes in Epic and/or by asking one of the patient's parents/clinicians;
  2. * Altered mental status that precludes ability to provide informed assent or consent (acute psychosis, intoxication, or mania);
  3. * Unable to provide informed consent (adults); assent (minors); permission (parents/caregivers).

Contacts and Locations

Study Contact

Holly C Wilcox, PhD
CONTACT
4103700081
hwilcox1@jhmi.edu
Taylor Ryan, MA
CONTACT
4846835824
tryan20@jh.edu

Principal Investigator

Holly C Wilcox, PhD
PRINCIPAL_INVESTIGATOR
Johns Hopkins Bloomberg School of Public Health

Study Locations (Sites)

Johns Hopkins All Children's Hospital
Saint Petersburg, Florida, 33701
United States
Johns Hopkins University
Baltimore, Maryland, 21205
United States
Columbia University Irving Medical Center (CUMC)
New York, New York, 10032
United States
Weill-Cornell Medicine
New York, New York, 10065
United States
University of North Carolina Medical Center
Chapel Hill, North Carolina, 27514
United States
Childrens Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: Johns Hopkins University

  • Holly C Wilcox, PhD, PRINCIPAL_INVESTIGATOR, Johns Hopkins Bloomberg School of Public Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-03-10
Study Completion Date2028-10-14

Study Record Updates

Study Start Date2025-03-10
Study Completion Date2028-10-14

Terms related to this study

Keywords Provided by Researchers

  • Safety Planning Intervention
  • Ultra-Brief Crisis
  • Interpersonal Psychotherapy for Adolescents
  • Emergency Department
  • Suicide Prevention

Additional Relevant MeSH Terms

  • Suicide, Attempted
  • Suicide Ideation
  • Suicide
  • Suicide Prevention