RECRUITING

COVID-19 Pharmacotherapy Effectiveness in the VA Healthcare System

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The purpose of this study is to comprehensively describe the temporal and geographic utilization of COVID-19 therapies used for mild to moderate disease during different periods of SARS-CoV-2 variant circulation as well as to compare demographic and clinical characteristics of Veterans who are treated or do not receive these different therapies. The investigators will also perform similar descriptive epidemiology for other respiratory viruses, including RSV and influenza and other infectious diseases. This first phase will critically inform feasibility and direction of the second phase, in which the investigators will use target trial emulation design to study the comparative effectiveness of therapies and vaccines for COVID-19, respiratory viruses, including RSV, and influenza, and other infectious diseases.

Official Title

CSP #2038 - COVID-19 Pharmacotherapy Effectiveness in the VA Healthcare System (COPE-VA)

Quick Facts

Study Start:2022-09-26
Study Completion:2027-09-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06160128

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * All Veterans aged 18 years alive and in VHA care as of January 2018.
  2. * Specific exclusion/inclusion criteria and observation periods will be further defined for each sub-study (See outcomes/publications).
  1. * VA employees who are not enrollees

Contacts and Locations

Study Contact

Kristina L Bajema, MD
CONTACT
(503) 220-8262
Kristina.Bajema@va.gov
George N Ioannou, MD MS
CONTACT
(206) 277-3136
George.Ioannou@va.gov

Principal Investigator

Kristina L Bajema, MD
STUDY_CHAIR
VA Portland Health Care System, Portland, OR
George N. Ioannou, MD MS
STUDY_CHAIR
VA Puget Sound Health Care System Seattle Division, Seattle, WA

Study Locations (Sites)

VA Portland Health Care System, Portland, OR
Portland, Oregon, 97207-2964
United States

Collaborators and Investigators

Sponsor: VA Office of Research and Development

  • Kristina L Bajema, MD, STUDY_CHAIR, VA Portland Health Care System, Portland, OR
  • George N. Ioannou, MD MS, STUDY_CHAIR, VA Puget Sound Health Care System Seattle Division, Seattle, WA

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2022-09-26
Study Completion Date2027-09-30

Study Record Updates

Study Start Date2022-09-26
Study Completion Date2027-09-30

Terms related to this study

Keywords Provided by Researchers

  • COVID-19
  • pharmacotherapy effectiveness
  • SARS-CoV-2
  • antiviral
  • RSV
  • influenza
  • respiratory viruses

Additional Relevant MeSH Terms

  • COVID-19, SARS-CoV-2 Infection
  • RSV
  • Influenza