Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

Description

This clinical trial investigates the role of contrast enhanced ultrasound (CEUS) in identifying cystic breast masses as benign or malignant. Ultrasound is a diagnostic imaging test that uses sound waves to make pictures of the body without using radiation (x-rays). Ultrasounds are widely used to diagnose many diseases in the body. This trial may help researchers learn if using CEUS will help in determining whether or not an ultrasound guided biopsy is necessary.

Conditions

Breast Carcinoma

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Study Overview

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Study Details

Study overview

This clinical trial investigates the role of contrast enhanced ultrasound (CEUS) in identifying cystic breast masses as benign or malignant. Ultrasound is a diagnostic imaging test that uses sound waves to make pictures of the body without using radiation (x-rays). Ultrasounds are widely used to diagnose many diseases in the body. This trial may help researchers learn if using CEUS will help in determining whether or not an ultrasound guided biopsy is necessary.

Characterizing Breast Masses Using an Integrative Framework of Machine Learning and Radiomics

Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses

Condition
Breast Carcinoma
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Los Angeles County-USC Medical Center, Los Angeles, California, United States, 90033

Los Angeles

USC / Norris Comprehensive Cancer Center, Los Angeles, California, United States, 90033

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Newly diagnosed breast masses assigned as BIRADS 4a, 4b, 4c or 5 by conventional US and recommended for ultrasound guided biopsy
  • * Age \>= 18 years
  • * Female
  • * Contraindications to microbubble contrast: Patients who have a known pulmonary hypertension and any known hypersensitivity to US contrast agent
  • * Women who are pregnant, possibly pregnant, or lactating
  • * Women currently undergoing neoadjuvant chemotherapy
  • * Women \< 18 years of age
  • * Masses in the same breast that had prior lumpectomy for cancer
  • * Women with cancer in the same breast will be excluded however, women with cancer in the contralateral breast will be eligible to participate in the study
  • * Women with an allergy to perflutren
  • * Prior history of biopsy for that specific lesion

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Southern California,

Bino A Varghese, PhD, PRINCIPAL_INVESTIGATOR, University of Southern California

Study Record Dates

2025-11-05