Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation

Description

The purpose of this clinical trial is to assess if the addition of DFDBA fibers to DBBM results in greater vital bone formation than the addition of DFDBA particles to DBBM. The study team will examine the effects of the addition of DFDBA fibers to DBBM on vital bone formation. Specifically, we will assess histologically the percent vital bone formation with each of the groups during implant placement, six months after the sinus augmentation procedure. We will also evaluate the radiographic volume achieved with both groups of materials.

Conditions

Bone Loss in Jaw

Study Overview

Study Details

Study overview

The purpose of this clinical trial is to assess if the addition of DFDBA fibers to DBBM results in greater vital bone formation than the addition of DFDBA particles to DBBM. The study team will examine the effects of the addition of DFDBA fibers to DBBM on vital bone formation. Specifically, we will assess histologically the percent vital bone formation with each of the groups during implant placement, six months after the sinus augmentation procedure. We will also evaluate the radiographic volume achieved with both groups of materials.

Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation: A Double Arm Randomized Control And Histomorphometric Study

Demineralized Bone Allograft Fibers Versus Particulate In Sinus Augmentation

Condition
Bone Loss in Jaw
Intervention / Treatment

-

Contacts and Locations

San Antonio

University of Texas Health Science Center at San Antonio, San Antonio, Texas, United States, 78229

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients between age 18 and 89
  • * Patients needing sinus augmentation to support implant placement in the posterior maxilla
  • * Patients must be nonsmokers, former smokers, or current smokers who smoke \<10 cigarettes per day, by self-report
  • * Female patients who have undergone a hysterectomy, tubal ligation, or menopause, and non- pregnant women of child-bearing potential.
  • * Patients who disclose that they will not be able to cooperate with the follow-up schedule.
  • * Patients who are mentally incompetent, prisoners, or pregnant (as obtained via chart review or self-report)
  • * Pregnant women or women intending to become pregnant during study period
  • * Smokers who smoke \> 10 cigarettes per day

Ages Eligible for Study

18 Years to 89 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

The University of Texas Health Science Center at San Antonio,

Angela Palaiologou-Gallis, DDS, MS, PRINCIPAL_INVESTIGATOR, The University of Texas Health Science Center at San Antonio

Study Record Dates

2026-05