RECRUITING

Transitional Care Program for Fluid Overload in Cirrhosis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn about an intensive monitoring plan (transitional care program) in patients with cirrhosis and excessive swelling that are going to be discharged from the hospital. The main question\[s\] it aims to answer are: * How much time and what resources are needed to run such a program * How well do patients follow up with the phone calls, bloodwork, and doctor appointments? * Do the patients enrolled in the program have less need for hospitalization later, less kidney injury, better fluid control, and/or better survival compared to patients that are not in the program? Participants will * Be given a digital scale and a binder with educational material and a log to monitor their weights after discharge from the hospital * Receive a phone call from the study team within 72 hours of discharge and weekly * Be given a follow up appointment with hepatology within 4 weeks of discharge Researchers will compare participants in this program to patients that receive normal care to see if there are differences in need for hospitalization later, kidney injury, fluid control, and/or survival.

Official Title

Transitional Care Program vs Standard of Care in Cirrhosis With Volume Overload: A Pilot Study

Quick Facts

Study Start:2025-01-01
Study Completion:2026-06-01
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06174272

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Patients \> 18 years of age.
  2. * Inpatient at Penn State Health, Milton S. Hershey Medical Center.
  3. * Diagnosis of cirrhosis.
  4. * Hospitalized with fluid overload (ascites and/or significant anasarca/edema) requiring diuretic therapy.
  5. * English speaking
  1. * Placement of a TIPS.
  2. * Ascites from an etiology other than cirrhosis, such as malignancy, heart failure, pancreatitis, nephrotic syndrome.
  3. * Non-English speaking

Contacts and Locations

Study Contact

Karen L Krok, MD
CONTACT
7175311017
kkrok@pennstatehealth.psu.edu
Shannon F Dalessio
CONTACT
7175310003
sdalessio@pennstatehealth.psu.edu

Principal Investigator

Karen L Krok, MD
PRINCIPAL_INVESTIGATOR
Penn State College of Medicine

Study Locations (Sites)

Penn State Milton S. Hershey Medical Center
Hershey, Pennsylvania, 17033
United States

Collaborators and Investigators

Sponsor: Milton S. Hershey Medical Center

  • Karen L Krok, MD, PRINCIPAL_INVESTIGATOR, Penn State College of Medicine

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-01
Study Completion Date2026-06-01

Study Record Updates

Study Start Date2025-01-01
Study Completion Date2026-06-01

Terms related to this study

Keywords Provided by Researchers

  • ascites
  • anasarca
  • edema

Additional Relevant MeSH Terms

  • Cirrhosis, Liver