RECRUITING

Chronic Remote Ischemic Conditioning in Vascular Cognitive Impairment: A Dose Escalation Study

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To evaluate the dose-response of relevant blood biomarkers to remote ischemic conditioning in patients with age-related cerebral white matter hyperintensities on MRI, in preparation for a subsequent larger efficacy trial.

Official Title

Chronic Remote Ischemic Conditioning in Vascular Cognitive Impairment: A Dose Escalation Study

Quick Facts

Study Start:2020-08-15
Study Completion:2023-12-15
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06179797

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:56 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age ≥55 years
  2. 2. Head MRI in the past 6 months showing no more than moderate age related cerebral white matter changes (Fazekas score 0-2).
  3. 3. Able to walk without assistance \& independently perform basic activities of daily living.
  4. 4. Able to understand this study and agree for a valid consent.
  1. 4. Contraindication to transient arm ischemia in either arm (such as symptomatic peripheral artery disease).

Contacts and Locations

Study Contact

Askiel Bruno, MD
CONTACT
706-721-1691
abruno@augusta.edu

Principal Investigator

Carol Smith, RN
STUDY_DIRECTOR
Wellstar MCG Health

Study Locations (Sites)

Wellstar MCG Health
Augusta, Georgia, 30912
United States

Collaborators and Investigators

Sponsor: Augusta University

  • Carol Smith, RN, STUDY_DIRECTOR, Wellstar MCG Health

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2020-08-15
Study Completion Date2023-12-15

Study Record Updates

Study Start Date2020-08-15
Study Completion Date2023-12-15

Terms related to this study

Additional Relevant MeSH Terms

  • Age-related Cerebral White Matter Changes
  • Cognition Disorder