Intravenous Fluids in Pediatric Migraine

Description

The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: * Does a large amount of fluids (bolus) improve pain * Does a large amount of fluids (bolus) reduce admissions to the hospital for migraine Participants will be asked to report their pain and have vital signs checked every 30 minutes for two hours. Researchers will compare a large amount of fluids (bolus) to a small amount (half maintenance) to see if there is a difference in pain improvement.

Conditions

Migraine, Migraine in Children

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Study Overview

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Study Details

Study overview

The goal of this clinical trial is to compare intravenous (IV) fluids in pediatric patients with migraine. The main questions it aims to answer are: * Does a large amount of fluids (bolus) improve pain * Does a large amount of fluids (bolus) reduce admissions to the hospital for migraine Participants will be asked to report their pain and have vital signs checked every 30 minutes for two hours. Researchers will compare a large amount of fluids (bolus) to a small amount (half maintenance) to see if there is a difference in pain improvement.

Value of Intravenous Fluids in the Emergent Treatment of Pediatric Migraine

Intravenous Fluids in Pediatric Migraine

Condition
Migraine
Intervention / Treatment

-

Contacts and Locations

Dayton

Dayton Children's Hosptial, Dayton, Ohio, United States, 45404

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * At least 1 prior headache
  • * Minimum pain score of 10mm
  • * Headache lasting 2-72 hours
  • * At least two of the following four: 1 Bifrontal/bitemporal or unilateral location, 2 Pulsating quality, 3 Moderate or severe pain intensity, 4 Aggravation by or causing avoidance of routine physical activity
  • * At least one of the following: 1 Nausea and/or vomiting, 2Photophobia and phonophobia, 3 Not better accounted for by another ICHD-3 diagnosis
  • * Shunted hydrocephalus
  • * Temperature equal to or greater than 38.5C
  • * Clinical suspicion of meningitis
  • * Known or suspected intracranial lesion
  • * Clinical evidence of significant dehydration (or signs of shock, or attending discretion)
  • * Head trauma in previous 7 days
  • * Pregnancy or breastfeeding
  • * Initial pain score less than 10mm
  • * Allergy to study medications
  • * Patients previously participating in the study

Ages Eligible for Study

5 Years to 21 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Dayton Children's Hospital,

Jonathan Elliott, MD, PRINCIPAL_INVESTIGATOR, Dayton Children's

Study Record Dates

2025-06