Anticipating Decline and Providing Therapy

Description

This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening and support intervention. The trial aims to enroll 120 older adults (age 60 or older).

Conditions

Cognitive Impairment, Dementia, Post ICU Syndrome, Critical Illness, Cognitive Impairment, Mild

Study Overview

Study Details

Study overview

This pilot feasibility study will be a randomized control trial of usual care following Intensive Care Unit (ICU) discharge compared to the Anticipating Decline and Providing Therapy (ADAPT) screening and support intervention. The trial aims to enroll 120 older adults (age 60 or older).

Anticipating Decline and Providing Therapy (ADAPT): Post-ICU Cognitive Screening Pilot and Feasibility Randomized Controlled Trial

Anticipating Decline and Providing Therapy

Condition
Cognitive Impairment
Intervention / Treatment

-

Contacts and Locations

Winston-Salem

Atrium Health Wake Forest Baptist, Winston-Salem, North Carolina, United States, 27157

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 60 and older at time of discharge from intensive care unit
  • * Minimum 72 hour Intensive Care Unit stay in an ICU at Atrium Health Wake Forest Baptist
  • * Delirium during ICU stay as determined by positive Confusion Assessment Method (CAM)-ICU score, review of clinical - documentation, or discussion with clinical team
  • * Primary care provider in the Atrium Health Wake Forest system or intention to follow with Primary Care Physician in Atrium Health system
  • * English speaking
  • * Death during initial hospitalization and/or discharge to Hospice
  • * Life-expectancy \< 6 months from pre-existing illness (defined as diagnosis of metastatic cancer, cirrhosis, advanced heart failure, prior palliative care referral)
  • * Acute Traumatic Brain Injury
  • * Continued residence in skilled nursing facility or rehab that prevents ability to complete study telephone call at time of first cognitive screen attempt
  • * Prior history of dementia in electronic health record
  • * Language or communication barrier that prohibits intervention participation
  • * Participant cannot identify family or caregiver contact or family/caregiver unwilling to participate
  • * Subject or legally authorized representative (LAR) decline consent
  • * Unstable telephone service for contact after hospital discharge
  • * Primary residence outside of North Carolina

Ages Eligible for Study

60 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Wake Forest University Health Sciences,

Jessica Palakshappa, MD, PRINCIPAL_INVESTIGATOR, Wake Forest University Health Sciences

Study Record Dates

2027-03