RECRUITING

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop and validate blood biomarkers that are specific to OSA, useful for identification of cases with OSA, reflective of efficacy of therapy, and able to predict blood pressure response to treatment of OSA.

Official Title

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

Quick Facts

Study Start:2024-04-01
Study Completion:2028-04-30
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06189755

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 75 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Not specified
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. Age 18 years or older
  2. Willing and able to provide informed consent
  3. Able to understand and follow study procedures
  4. Stable medical condition
  1. Pregnancy or breastfeeding
  2. Severe psychiatric disorders
  3. Active substance abuse
  4. Unstable medical conditions
  5. Inability to comply with study requirements

Contacts and Locations

Study Contact

Colleen M Walsh, MS
CONTACT
215-614-0047
walshco@pennmedicine.upenn.edu
Kristie C Nguyen
CONTACT
215-615-4112
kristie.nguyen@pennmedicine.upenn.edu

Principal Investigator

Allan I Pack, MBChB, PhD
PRINCIPAL_INVESTIGATOR
University of Pennsylvania

Study Locations (Sites)

The Ohio State University - Martha Morehouse Medical Pavilion, Suite 2600
Columbus, Ohio, 43221
United States
University of Pennsylvania
Philadelphia, Pennsylvania, 19104
United States

Collaborators and Investigators

Sponsor: University of Pennsylvania

  • Allan I Pack, MBChB, PhD, PRINCIPAL_INVESTIGATOR, University of Pennsylvania

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-04-01
Study Completion Date2028-04-30

Study Record Updates

Study Start Date2024-04-01
Study Completion Date2028-04-30

Terms related to this study

Keywords Provided by Researchers

  • Sleep Apnea
  • Biomarkers
  • Blood pressure

Additional Relevant MeSH Terms

  • Obstructive Sleep Apnea