Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

Description

This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different types of anesthesia. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of anesthetics for the exam are in clinical equipoise are asked to join the study. All eligible subjects will be asked to provide informed consent before participating in the study.

Conditions

HIE, TBI (Traumatic Brain Injury), TBI, Hemodynamic Instability, Hypoxic-Ischemic Encephalopathy

Study Overview

Study Details

Study overview

This is an observational study in patients who require clinical anesthesia. The main purpose of this study is to understand whether there are differences in the cerebral blood flow, and oxygen metabolism affected by different types of anesthesia. Subjects who require clinical anesthesia for a clinical MRI and for whom the use of anesthetics for the exam are in clinical equipoise are asked to join the study. All eligible subjects will be asked to provide informed consent before participating in the study.

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

Individual Cerebral Hemodynamic Oxygenation Relationships (ICHOR 1)

Condition
HIE
Intervention / Treatment

-

Contacts and Locations

Los Angeles

Children's Hospital Los Angeles, Los Angeles, California, United States, 90027

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Individuals who are able to tolerate an MRI.
  • * Are patients scheduled for a clinically indicated MRI.
  • * Between birth and up to 18 years.
  • * Presence of an MRI-incompatible device or implant (e.g. pacemakers, stents)
  • * Unable to tolerate the enclosed spaces and loud noises for the duration of time in scanner required to obtain an MRI.
  • * Preterm infants less than 25 weeks
  • * Any patient who is clinically too unstable to extend their MRI by up-to 7.5 minutes.

Ages Eligible for Study

1 Minute to 18 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Children's Hospital Los Angeles,

Study Record Dates

2025-11