Feasibility Trial Using an Inpatient Insulin Dosing Calculator

Description

The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are: * Whether using this calculator leads to no excessive hypoglycemia? * Whether using this calculator leads to a decrease of hyperglycemia? Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.

Conditions

Diabetes Mellitus, Type 2

Study Overview

Study Details

Study overview

The goal of this feasibility trial is to test whether a novel insulin dosing calculator can improve blood glucose management for patients with type 2 diabetes mellitus on hospital admission. The main questions it aims to answer are: * Whether using this calculator leads to no excessive hypoglycemia? * Whether using this calculator leads to a decrease of hyperglycemia? Participants will receive initial insulin doses by the calculator on hospital admission, and the rest of care will follow standard of care. Participants will be compared with patients in the UW observational cohort who received initial insulin doses by standard of care.

Feasibility Trial Using an Insulin Dosing Calculator for Patients With Type 2 Diabetes Mellitus on Hospital Admission

Feasibility Trial Using an Inpatient Insulin Dosing Calculator

Condition
Diabetes Mellitus, Type 2
Intervention / Treatment

-

Contacts and Locations

Seattle

Harborview Medical Center, Seattle, Washington, United States, 98104

Seattle

UW Medical Center - Northwest, Seattle, Washington, United States, 98133

Seattle

UW Medical Center - Montlake, Seattle, Washington, United States, 98195

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients who are admitted to University of Washington Medical Centers
  • * With history of type 2 and/or steroid-induced diabetes mellitus
  • * Receiving insulin therapy prior to admission
  • * Patients who are admitted to ICU or obstetrics ward
  • * Patients who are admitted for elective surgery or procedure
  • * Patients who present with diabetic ketone acidosis, hyperosmolar hyperglycemic state or require intravenous insulin infusion
  • * Patients who have no meal intake for 24 hours prior to admission, or planned nothing per oral (NPO) during the first 24 hours after admission
  • * Patients who report low appetite (25% or less) on admission or have a significantly decreased level of consciousness that they unlikely eat right after admission
  • * Patients who receive enteral feeding after admission

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Washington,

Hou-Hsien Chiang, MD, PhD, PRINCIPAL_INVESTIGATOR, University of Washington

Study Record Dates

2025-02