COMPLETED

The Effects of Chiropractic in a Population With High Central Adiposity

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Since 1980, the global prevalence of obesity, commonly defined as a body mass index (BMI) of 30 or higher, has doubled. Importantly, high levels of central adiposity (i.e., abdominal fat) is associated with numerous PNI-related sequelae, including increased levels of psychological distress, cognitive deficits, ANS dysfunction, and immune marker abnormalities. To our knowledge, rigorous investigation of chiropractic's impact on psychoneuroimmunological (PNI)-related outcomes in people with high central adiposity is lacking. Based on limited evidence to date, it is plausible that clinically important PNI-related dysfunctions (e.g., heightened stress levels, executive function impairments, dysautonomia, immune dysregulation) common in this population could be ameliorated via chiropractic care.

Official Title

Psychoneuroimmunology as a Framework for Studying the Effects of Chiropractic Care in a Population With High Central Adiposity: a Feasibility Trial

Quick Facts

Study Start:2024-11-04
Study Completion:2025-09-04
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06208163

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 65 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * 18-65 years of age
  2. * Body mass index (BMI) at least 30
  3. * Waist circumference at least 35 inches if female or 40 inches if male
  1. * Had chiropractic care within the past 30 days
  2. * Prescribed short-acting benzodiazepines which include midazolam \& triazolam
  3. * If taking prescription medications, other than short-acting benzodiazepines, not on a stable dose for a minimum of 6 weeks with plans to change medications or doses during the study
  4. * Not able to walk unassisted on a treadmill
  5. * Known disorder resulting in syncope/fainting during postural changes (e.g., POTS, orthostatic hypotension)
  6. * Pacemaker or known heart condition that influences the electrical or mechanical function of the heart (e.g., severe heart valve disease)
  7. * Diagnosed with externalizing (e.g., substance use, antisocial disorder) or thought (e.g., schizophrenia, paranoid personality, bipolar) disorder that is uncontrolled or untreated
  8. * Diagnosed with rheumatoid arthritis, osteoporosis, or cervical spine instability
  9. * Hearing impairment (cognitive task uses auditory stimuli)
  10. * Currently pregnant
  11. * Current litigation related to a physical, health-related injury
  12. * Whiplash injury in the past 3 months
  13. * Oral injury, inflammation, or disease that causes the mouth or gums to bleed easily

Contacts and Locations

Principal Investigator

Tyson Perez, DC, PhD
PRINCIPAL_INVESTIGATOR
Life University

Study Locations (Sites)

Dr. Sid E. Williams Center for Chiropractic Research
Marietta, Georgia, 30067
United States

Collaborators and Investigators

Sponsor: Life University

  • Tyson Perez, DC, PhD, PRINCIPAL_INVESTIGATOR, Life University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-11-04
Study Completion Date2025-09-04

Study Record Updates

Study Start Date2024-11-04
Study Completion Date2025-09-04

Terms related to this study

Keywords Provided by Researchers

  • abdominal obesity
  • adults
  • psychoneuroimmunology
  • chiropractic

Additional Relevant MeSH Terms

  • Abdominal Obesity