RECRUITING

EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation

Talk to us

Conditions

Paroxysmal Atrial FibrillationCatheter ablationExercise capacity

Quick Navigation

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Longitudinal, observational cohort study to evaluate changes in left atrial (LA) reservoir function during exercise and overall exertional capacity in patients following catheter ablation for paroxysmal atrial fibrillation (AF).

Official Title

EXCLAMATORY: EXercise Cardiac Magnetic Resonance Assessment of Left Atrial Mechanics Following Ablation TO Reduce Atrial Fibrillation Burden and Correlation With Exercise CapacitY Longitudinal Study

Quick Facts

Study Start:2024-12-30
Study Completion:2028-03
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06212791

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Age ≥18 years
  2. * Diagnosis of paroxysmal AF
  3. * Left ventricular ejection fraction ≥50%
  4. * Scheduled for catheter ablation
  5. * Able to speak, hear, and read English
  6. * Willing and able to provide informed consent
  1. * Persistent or permanent AF
  2. * Prior ablation (catheter based or surgical) for AF
  3. * Significant sinus node dysfunction
  4. * Implanted pacemaker or defibrillator
  5. * Contraindication to or inability to complete cardiovascular magnetic resonance study
  6. * Contraindication to or inability to complete exercise testing
  7. * Chronic kidney disease with estimated glomerular filtration rate \<30 mL/min/1.73m2
  8. * Severe left ventricular hypertrophy
  9. * Unrelated cardiomyopathy that is expected to limit exercise capacity, including but not limited to:
  10. * Hypertrophic cardiomyopathy
  11. * Cardiac amyloidosis
  12. * Constrictive pericarditis
  13. * Pulmonary arterial hypertension
  14. * Prior cardiac surgery
  15. * Active pregnancy

Contacts and Locations

Study Contact

Pamela Grizzard
CONTACT
804-628-6234
pamela.grizzard@vcuhealth.org
Melissa Sears
CONTACT
804-828-1601
melissa.sears@vcuhealth.org

Principal Investigator

Cory Trankle
PRINCIPAL_INVESTIGATOR
Virginia Commonwealth University

Study Locations (Sites)

Virginia Commonwealth University
Richmond, Virginia, 23298
United States

Collaborators and Investigators

Sponsor: Virginia Commonwealth University

  • Cory Trankle, PRINCIPAL_INVESTIGATOR, Virginia Commonwealth University

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-30
Study Completion Date2028-03

Study Record Updates

Study Start Date2024-12-30
Study Completion Date2028-03

Terms related to this study

Keywords Provided by Researchers

  • Catheter ablation
  • Exercise capacity

Additional Relevant MeSH Terms

  • Paroxysmal Atrial Fibrillation