Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

Description

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Conditions

Hypertension, Pregnancy-Induced

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Study Overview

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Study Details

Study overview

The long-term goal of our work is to evaluate the effect of intensive postpartum blood pressure control on maternal cardiovascular health, risk of chronic hypertension, and reversal of vascular dysfunction generated by hypertensive disorders of pregnancy, thus attenuating the lifelong trajectory of cardiovascular disease risk.

Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following

Reducing the Risk of Chronic Hypertension and Improving Vascular Function Following Preeclampsia

Condition
Hypertension, Pregnancy-Induced
Intervention / Treatment

-

Contacts and Locations

Chicago

Northwestern University, Chicago, Illinois, United States, 60611

Milwaukee

Medical College of Wisconsin, Milwaukee, Wisconsin, United States, 53226

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Hypertensive disorders of pregnancy (HDP) diagnosis, specifically gestational hypertension or preeclampsia, according to ACOG guidelines
  • * Postpartum day 0-4
  • * Able to communicate in English or in Spanish
  • * Has an established OBGYN at an MCW or NU health system practice that has access to Epic electronic medical records.
  • * Pre-gestational hypertension
  • * Type 1 or type 2 diabetes mellitus
  • * Admitted to intensive care unit at the time of screening
  • * Diagnosed with HDP during postpartum readmission after discharge from delivery hospitalization
  • * Getting discharged on the day of screening
  • * Known allergy or contraindication to nifedipine ER
  • * Inability or unwillingness to provide informed consent

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

Medical College of Wisconsin,

Anna Palatnik, MD, PRINCIPAL_INVESTIGATOR, Medical College of Wisconsin

Study Record Dates

2030-06-30