RECRUITING

Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Determine the levels of Donor-derived (dd)cell-free DNA(cfDNA )in liver transplant recipients with normal liver function tests (LFTs) indicating stable immunosuppression status (IS). Based on this range use the dd-cfDNA levels to determine over or under IS in liver transplant patients to make changes to their IS medication regimen.

Official Title

Retrospective Exploratory Analysis of Donor-derived Cell Free DNA in Liver Transplant Patients

Quick Facts

Study Start:2021-07-01
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06225206

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. 1. Age: ≥18 years
  2. 2. The patient underwent a liver transplant.
  3. 3. The patient at least has one level of dd-cfDNA documented
  1. * Patient not meeting the inclusion criteria will be excluded.

Contacts and Locations

Study Contact

Kavya Vinod Mankulangara, PharmD
CONTACT
214-947-4681
MHSIRB@mhd.com
Bethany Brauer, MPH
CONTACT
214-947-4681
mhsirb@mhd.com

Principal Investigator

Parvez Mantry, MD
PRINCIPAL_INVESTIGATOR
Methodist Midlothian Medical Center

Study Locations (Sites)

Methodist Dallas Medical Center
Dallas, Texas, 75203
United States

Collaborators and Investigators

Sponsor: Methodist Health System

  • Parvez Mantry, MD, PRINCIPAL_INVESTIGATOR, Methodist Midlothian Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-07-01
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2021-07-01
Study Completion Date2024-12-31

Terms related to this study

Additional Relevant MeSH Terms

  • Liver Transplant Failure