COMPLETED

Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn about how fatigue affects the risk of falling in adults aged 55-70 years with and without knee osteoarthritis. The main questions this trial aims to answer are: * Does fatigue increase the risk of tripping while walking? and * Does fatigue increase the risk of falling in response to a trip while walking? Participants will * Complete questionnaires * Wear a device that measures physical activity for 5-7 days * Complete a 30 minute walk on a treadmill * Complete the following before and after the treadmill walk: * Computer test to measure mental fatigue * Maximal strength testing * Balance test Researchers will compare adults with and without knee osteoarthritis to see if fall risk in adults with knee osteoarthritis is affected more by walking activity compared to adults without knee osteoarthritis.

Official Title

Muscle Fatigability and Trip-specific Fall Risk in Adults With Knee Osteoarthritis

Quick Facts

Study Start:2024-05-14
Study Completion:2025-08-27
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:COMPLETED

Study ID

NCT06229691

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:55 Years to 70 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * presence of occasional to frequent knee pain
  2. * knee pain that is primarily in the medial knee joint compartment
  3. * minimal morning joint stiffness
  4. * able to walk continuously for 30 minutes without an assistive device
  1. * fracture or surgery within 1 year
  2. * history of joint replacement
  3. * lower-extremity joint injections within 3 months
  4. * history of stroke or other neurological condition
  5. * cardiovascular or pulmonary conditions that limit daily activity or that preclude participation in exercise
  6. * history of major lower extremity or back injury or pain (except for knee osteoarthritis)
  7. * history of lower extremity amputation
  8. * use an orthotic or prosthetic to walk
  9. * use of beta blockers or other medications that affect fatigue
  10. * use of medications that affect balance
  11. * diabetic neuropathy
  12. * acute illness or the presence of lesions on the torso or lower extremities
  13. * BMI greater than 35
  14. * body weight over 265 lbs

Contacts and Locations

Study Locations (Sites)

University of Delaware
Newark, Delaware, 19713
United States

Collaborators and Investigators

Sponsor: University of Delaware

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-05-14
Study Completion Date2025-08-27

Study Record Updates

Study Start Date2024-05-14
Study Completion Date2025-08-27

Terms related to this study

Keywords Provided by Researchers

  • balance
  • fatigue
  • falls

Additional Relevant MeSH Terms

  • Osteoarthritis, Knee