Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

Description

This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years and older with elevated blood pressure. Participants will perform IMST for 5 minutes a day, 6 days a week, for 6 weeks.

Conditions

Blood Pressure, Vascular Function, Adherence, Treatment

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Study Overview

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Study Details

Study overview

This clinical trial aims to assess the efficacy of inspiratory muscle strength training (IMST) guided by a smartphone app vs. IMST delivered in a clinical research setting for lowering systolic blood pressure in adults 18 years and older with elevated blood pressure. Participants will perform IMST for 5 minutes a day, 6 days a week, for 6 weeks.

Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

Smartphone App-guided Inspiratory Muscle Strength Training for Lowering Systolic Blood Pressure

Condition
Blood Pressure
Intervention / Treatment

-

Contacts and Locations

Boulder

University of Colorado Boulder, Boulder, Colorado, United States, 80309

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Age 18+ years
  • * Ability to provide informed consent
  • * Willing to accept random assignment to condition
  • * Systolic blood pressure 120-160 mmHg
  • * Owns an Apple or Android smartphone
  • * Body mass index \<40 kg/m2
  • * Subject report of being weight stable in the prior 3 months (\<2 kg weight change) and willing to remain weight stable during the 6-week intervention period
  • * Subjects taking antihypertensive medications will be included provided they meet the other inclusion criteria, including systolic blood pressure. Medication regimen (prescription and dosing) must be stable for at least 3 months prior to enrollment in the study and must remain stable during the 6-week intervention period. These medications will not be withheld prior to experimental protocols.
  • * If woman of childbearing age:
  • * Not pregnant (defined as self-report of pregnancy)
  • * Willing to be abstinent or use approved contraception (i.e., hormonal contraception, intrauterine devices, barrier methods such as condoms with spermicide, and surgical sterilization) throughout the duration of the study
  • * Age \<18 years
  • * Participant report of a chronic overt medical condition (e.g., unstable cardiovascular disease, recent myocardial infarction or stroke, cancer) that may make it unsafe to participate in the study under the discretion of the study Medical Director.
  • * Inability to abstain from consumption of alcohol for 12 hours on experimental days.
  • * Report of blood donation within 8 weeks prior to enrolling in the study or unwillingness to abstain from donating blood for 8 weeks after completing the study
  • * Participant report of current ruptured eardrum or any other current condition of the ear
  • * Participant report of recent abdominal surgery (past 3 months) or current abdominal hernia
  • * Participant report of current asthma with very low symptom perception, frequent and severe exacerbations, or abnormally low perception of dyspnea
  • * Participant report of past or current costochondritis (inflammation of the cartilage that joins the ribs to the breastbone)

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

University of Colorado, Boulder,

Daniel H Craighead, PhD, PRINCIPAL_INVESTIGATOR, University of Colorado, Boulder

Study Record Dates

2025-11-30