RECRUITING

Speech Pattern Evaluation and Analysis for Knowledge of AD

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this observational study is to validate changes in speech as a measure of cognition in individuals at increased risk of Alzheimer's disease and related dementias (ADRD). This study aims to clarify how speech may be affected by Alzheimer's disease. Participants will complete speech collection sessions and a survey at home using an iPad. Participants can expect to be in the study for 3 years.

Official Title

Connected Language and Speech Along the Spectrum of ADRD: Digital Assessment and Monitoring

Quick Facts

Study Start:2025-01-22
Study Completion:2029-02
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06230783

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:40 Years to 80 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Must be enrolled in the Wisconsin Alzheimer's Disease Research Center (W-ADRC) Clinical Core or IMPACT studies, or in the Wisconsin Registry for Alzheimer's Prevention (WRAP)
  2. * Cognitively unimpaired or have a diagnosis of Mild Cognitive Impairment (MCI)
  3. * Ages 40-80 years
  4. * Completion of a W-ADRC or WRAP study visit within the past or upcoming 12 months
  5. * Have provided W-ADRC or WRAP with blood plasma Alzheimer's Disease
  1. * Not actively enrolled in W-ADRC or WRAP
  2. * Diagnosis of dementia
  3. * Impaired capacity or unwilling to consent
  4. * Major neurological conditions
  5. * Speech disorders

Contacts and Locations

Study Contact

Leah K Sanson-Miles
CONTACT
608-262-7497
lsanson@wisc.edu

Principal Investigator

Kimberly D Mueller, PhD, CCC-SLP
PRINCIPAL_INVESTIGATOR
University of Wisconsin, Madison

Study Locations (Sites)

University of Wisconsin
Madison, Wisconsin, 53705
United States

Collaborators and Investigators

Sponsor: University of Wisconsin, Madison

  • Kimberly D Mueller, PhD, CCC-SLP, PRINCIPAL_INVESTIGATOR, University of Wisconsin, Madison

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2025-01-22
Study Completion Date2029-02

Study Record Updates

Study Start Date2025-01-22
Study Completion Date2029-02

Terms related to this study

Additional Relevant MeSH Terms

  • Wisconsin Alzheimer's Disease Research Center
  • Wisconsin Registry for Alzheimer's Prevention