Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Description

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

Conditions

Maxillary Sinus Floor Augmentation, Dental Implant, Bone Substitute, Autogenous Bone Graft

Talk to us

Study Overview

On this page

Study Details

Study overview

To evaluate bone healing at 4 months after lateral sinus augmentation with a 4:1 ratio of autologous bone and xenograft or xenograft alone. A radiographic volumetric, histomorphometric, and histologic analysis.

Sinus Augmentation Healing With Autogenous and Xenograft Mix Compared to Xenograft Alone

Evaluation of Sinus Augmentation Bone Healing Using Autograft and Xenograft Compared to Xenograft Alone

Condition
Maxillary Sinus Floor Augmentation
Intervention / Treatment

-

Contacts and Locations

Boston

Tufts University School of Dental Medicine, Boston, Massachusetts, United States, 02111

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Patients of Tufts School of Dental Medicine (TUSDM)
  • * Two stage sinus augmentations with \<5mm (Zinner, Small 2004) residual bone height in need of augmentation for implant placement
  • * Full maxillary edentulism or Kennedy class I or III
  • * 18 to 100 year old
  • * Adults unable to consent (cognitively impaired adults)
  • * Those who self-report as pregnant or breastfeeding
  • * Wards of the state
  • * Non-Viable neonates
  • * Neonates of uncertain viability
  • * \< 18 years of age
  • * Refusal to participate
  • * Prior medical condition causing complications in bone metabolism
  • * Osteoporosis
  • * History of/or current chemotherapy
  • * History of/or current head and neck radiation
  • * Current heavy smoking \> 10 cigarettes/day
  • * Self-reported pregnancy or lactation
  • * Previous history of sinus elevation procedure
  • * Existing sinus pathology or pathology discovered at time of sinus augmentation or implant placement
  • * Absence of autogenous donor site

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Tufts University,

Lorenzo Mordini, DDS, MS, PRINCIPAL_INVESTIGATOR, Tufts Univeristy

Study Record Dates

2028-05