To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

Description

The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise? Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there are significant differences in resting heart rate, systolic blood pressure (SBP), and A1c levels in the blood.

Conditions

Stroke, Walking, Difficulty, Cardiovascular Injury

Study Overview

Study Details

Study overview

The goal of this clinical trial is to test a gait (walking) training program in non-ambulatory (unable to walk) chronic stroke survivors. The main question it aims to answer is: • Will gait training improve the cardiovascular system in non-ambulatory chronic stroke survivors better than a sitting leg cycling exercise? Participants will walk on a treadmill with a partial body-weight support system and the gait training device. Researchers will compare with a leg-cycling exercise to see if there are significant differences in resting heart rate, systolic blood pressure (SBP), and A1c levels in the blood.

To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

To Develop a Walking Exercise Program for Non-ambulatory Stroke Survivors

Condition
Stroke
Intervention / Treatment

-

Contacts and Locations

Kansas City

University of Kansas Medical Center, Kansas City, Kansas, United States, 66160

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * must be 18 to 80 years old
  • * male or female
  • * independent ambulation before stroke
  • * able to understand and follow verbal commands in English
  • * have physicians' approval for exercise
  • * be in a stable medical condition
  • * must be after the first stroke
  • * unable to walk independently
  • * in the chronic stage (at least 6 months after stroke onset)
  • * musculoskeletal or other disorders that prevent the participant from participating in the exercise
  • * blood pressure higher than 200/110 mm Hg
  • * diagnosis of severe depression
  • * functionally restricted passive movement in the major joints of lower limbs
  • * unable to speak or understand English
  • * unable to travel to the Research Laboratory
  • * currently participate in other walking training using treadmill with or without a body-weight support system
  • * body weight greater than 400 lbs

Ages Eligible for Study

18 Years to 80 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Kansas Medical Center,

Wen Liu, PhD, PRINCIPAL_INVESTIGATOR, University of Kansas Medical Center

Study Record Dates

2025-09-01