RECRUITING

Risk of Recurrent CeAD After Pregnancy

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

Primary objective: To determine whether pregnancy increases the risk of recurrent CeAD and delayed stroke in women with prior CeAD based on long-term data. Methods: Multicentric, observational case-control study based on pooled individual patient data from several stroke centers. Primary endpoint: Primary composite outcome measure includes the following outcomes: (i) occurrence of recurrent CeAD, (ii) occurrence of ischemic or hemorrhagic stroke, (iii) death.

Official Title

Long-term Risk of Recurrent Cervical Artery Dissection After Pregnancy (LONG-RECAP Study)

Quick Facts

Study Start:2023-01-01
Study Completion:2024-12-31
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06258109

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:FEMALE
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * female
  2. * prior symptomatic cervical artery dissection (= index CeAD)
  3. * at least one long-term follow-up visit (at least 6 months after the initial event)
  4. * with information available on outcome events:
  5. * recurrent dissection
  6. * ischemic stroke
  7. * hemorrhagic stroke
  8. * functional outcome assessed by mRS score
  9. * with data on pregnancy after the initial event
  10. * at least 18 years old at the initial event
  1. * Male patients
  2. * Age \<18 years
  3. * No long-term follow-up available or long-term follow-up \< 6 months after initial event
  4. * No data on pregnancy after initial event available

Contacts and Locations

Study Contact

Stefan T Engelter, MD
CONTACT
+41 61 326 41 05
stefan.engelter@felixplatter.ch
Sandro K Fischer
CONTACT
+41 61 328 47 84
sandrokevin.fischer@usb.ch

Principal Investigator

Stefan T Engelter, MD
PRINCIPAL_INVESTIGATOR
University Hospital, Basel, Switzerland

Study Locations (Sites)

University of Utah
Salt Lake City, Utah, 84112
United States
University of Virginia
Charlottesville, Virginia, 22908
United States

Collaborators and Investigators

Sponsor: University Hospital, Basel, Switzerland

  • Stefan T Engelter, MD, PRINCIPAL_INVESTIGATOR, University Hospital, Basel, Switzerland

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2023-01-01
Study Completion Date2024-12-31

Study Record Updates

Study Start Date2023-01-01
Study Completion Date2024-12-31

Terms related to this study

Keywords Provided by Researchers

  • Ischemic Stroke
  • Hemorrhagic Stroke

Additional Relevant MeSH Terms

  • Cervical Artery Dissection
  • Pregnancy Complications