Risk of Recurrent CeAD After Pregnancy

Description

Primary objective: To determine whether pregnancy increases the risk of recurrent CeAD and delayed stroke in women with prior CeAD based on long-term data. Methods: Multicentric, observational case-control study based on pooled individual patient data from several stroke centers. Primary endpoint: Primary composite outcome measure includes the following outcomes: (i) occurrence of recurrent CeAD, (ii) occurrence of ischemic or hemorrhagic stroke, (iii) death.

Conditions

Cervical Artery Dissection, Pregnancy Complications

Study Overview

Study Details

Study overview

Primary objective: To determine whether pregnancy increases the risk of recurrent CeAD and delayed stroke in women with prior CeAD based on long-term data. Methods: Multicentric, observational case-control study based on pooled individual patient data from several stroke centers. Primary endpoint: Primary composite outcome measure includes the following outcomes: (i) occurrence of recurrent CeAD, (ii) occurrence of ischemic or hemorrhagic stroke, (iii) death.

Long-term Risk of Recurrent Cervical Artery Dissection After Pregnancy (LONG-RECAP Study)

Risk of Recurrent CeAD After Pregnancy

Condition
Cervical Artery Dissection
Intervention / Treatment

-

Contacts and Locations

Salt Lake City

University of Utah, Salt Lake City, Utah, United States, 84112

Charlottesville

University of Virginia, Charlottesville, Virginia, United States, 22908

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * female
  • * prior symptomatic cervical artery dissection (= index CeAD)
  • * at least one long-term follow-up visit (at least 6 months after the initial event)
  • * with information available on outcome events:
  • * recurrent dissection
  • * ischemic stroke
  • * hemorrhagic stroke
  • * functional outcome assessed by mRS score
  • * with data on pregnancy after the initial event
  • * at least 18 years old at the initial event
  • * Male patients
  • * Age \<18 years
  • * No long-term follow-up available or long-term follow-up \< 6 months after initial event
  • * No data on pregnancy after initial event available

Ages Eligible for Study

18 Years to

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University Hospital, Basel, Switzerland,

Stefan T Engelter, MD, PRINCIPAL_INVESTIGATOR, University Hospital, Basel, Switzerland

Study Record Dates

2024-12-31