Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Description

This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as well as more traditional intoxication measures such as breath alcohol concentration and balance metrics. If eligible for the study, participants will be randomized to complete one study session in our mobile laboratory, during which they will use either alcohol, cannabis (which will be self-administered, ad libitum) or both alcohol and cannabis.

Conditions

Cannabis Use, Alcohol Use, Unspecified

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Study Overview

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Study Details

Study overview

This is a randomized, parallel-group study designed to explore the differences between cannabis intoxication, alcohol intoxication and co-intoxication involving both alcohol and cannabis, utilizing electroencephalography (EEG) as well as more traditional intoxication measures such as breath alcohol concentration and balance metrics. If eligible for the study, participants will be randomized to complete one study session in our mobile laboratory, during which they will use either alcohol, cannabis (which will be self-administered, ad libitum) or both alcohol and cannabis.

Developing Predictive Models to Distinguish Alcohol Use, Cannabis Use and Co-use: An Exploration of Electroencephalography (EEG) Metrics and Traditional Intoxication Measures

Distinguishing Alcohol Intoxication, Cannabis Intoxication and Co-intoxication Using Electroencephalography (EEG)

Condition
Cannabis Use
Intervention / Treatment

-

Contacts and Locations

Fort Collins

Colorado State University, Fort Collins, Colorado, United States, 80523

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * 21-50 years old
  • * Heavy drinkers (consuming more than 4 drinks/day or more than 14 drinks/week for men, or more than 3 drinks/day or more than 7 drinks/week for women)
  • * Regular users of legal-market flower cannabis (at least 2x/week in past 3 months)
  • * report simultaneously using alcohol and legal-market flower cannabis at least once per month in the past 3 months
  • * English speakers.
  • * Daily tobacco users
  • * Diagnosed with or seeking treatment for alcohol use disorder (AUD) or other substance use disorder (SUD)
  • * Females cannot be pregnant, breastfeeding or trying to become pregnant
  • * Meet criteria for psychotic, bipolar or major depressive disorder with suicidal ideation, or history of these disorders, 5) Current use of psychotropic (except anti-depressants)
  • * Report illicit drug use in past 60-days or fail drug screen on the day of the study appointment
  • * Major medical condition contraindicating alcohol and/or cannabis consumption.

Ages Eligible for Study

21 Years to 50 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Colorado State University,

Hollis Karoly, PhD, PRINCIPAL_INVESTIGATOR, Colorado State University

Patricia Davies, PhD, PRINCIPAL_INVESTIGATOR, Colorado State University

Study Record Dates

2026-05-30