Magnesium and Riboflavin Treatment for Post-Concussion Headache

Description

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

Conditions

Concussion, Intermediate

Study Overview

Study Details

Study overview

This clinical trial will try to determine if the supplements magnesium and riboflavin will reduce the pain and duration of headaches in persons diagnosed with a concussion. The participant will be randomized to either active magnesium and riboflavin capsules or placebo (inert) capsules. The capsules will be taken once a day for 14 days. The participant will also complete a short diary form for the 14 days and will have 3 follow up visits either by telephone or in person.

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Magnesium and Riboflavin Treatment for Post-Concussion Headache

Condition
Concussion, Intermediate
Intervention / Treatment

-

Contacts and Locations

Charlottesville

University of Virginia Student Health and Wellness Center, Charlottesville, Virginia, United States, 22903

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Seen at University of Virginia Student Health and Wellness Center or Emergency Department for Initial Visit for Concussion;
  • * Less than 3 days have elapsed since their injury;
  • * Able to swallow capsules
  • * Concussion complicated by cranial bleed, skull fracture, additional severe injury;
  • * Kidney disfunction or failure;
  • * Significant gastro-intestinal dysfunction;
  • * Varsity Athlete;
  • * Two or more previous concussions;
  • * Women who are pregnant or breast feeding;
  • * Taking tetracycline, fluoroquinolone, iron digoxin, chlorpromazine or penicillamine

Ages Eligible for Study

18 Years to 40 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Virginia,

Stephanie Hartman, MD, PRINCIPAL_INVESTIGATOR, UVA Student Health and Wellness

Study Record Dates

2024-12-31