A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

Description

This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers. ECs may reduce cigarette craving and withdrawal symptoms, increase motivation and confidence to stop cigarette smoking, and decrease cigarette smoking and dependence. By comparing participants' preferred flavor ECs (PEC) to tobacco flavor ECs (TEC) to NRT, researchers hope to determine the effect of EC flavors on appeal and use and learn how ECs affect smoking behaviors and health.

Conditions

Cigarette Smoking-Related Carcinoma

Talk to us

Study Overview

On this page

Study Details

Study overview

This clinical trial compares the use of tobacco flavored electronic cigarettes (ECs) vs. non-tobacco flavored ECs vs. nicotine replacement therapy (patches and lozenges) on smoking behavior in current cigarette smokers. ECs may reduce cigarette craving and withdrawal symptoms, increase motivation and confidence to stop cigarette smoking, and decrease cigarette smoking and dependence. By comparing participants' preferred flavor ECs (PEC) to tobacco flavor ECs (TEC) to NRT, researchers hope to determine the effect of EC flavors on appeal and use and learn how ECs affect smoking behaviors and health.

A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-Cigarettes on Smoking Behavior

A Comprehensive Evaluation of Tobacco-Flavored vs. Non-Tobacco Flavored E-cigarettes on Smoking Behavior

Condition
Cigarette Smoking-Related Carcinoma
Intervention / Treatment

-

Contacts and Locations

Columbus

Ohio State University Comprehensive Cancer Center, Columbus, Ohio, United States, 43210

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * \>= 21 years old
  • * Smoke \>= 5 cigarettes per day for the past year
  • * Willing to use either an EC or NRT
  • * Read and speak English
  • * Have a smartphone
  • * Report currently using smoking cessation medications, NRT, or actively seeking treatment for smoking cessation
  • * Current use of an EC \> 4 days a month
  • * Diagnosed medical conditions of lung disease, asthma, cystic fibrosis, heart disease or chronic obstructive pulmonary disease (COPD)
  • * Unmanaged (unmedicated and/or without counseling) diagnosis of schizophrenia
  • * History of cardiac event or distress within the past 3 months
  • * Currently pregnant, planning to become pregnant within 6 months, or breastfeeding
  • * High blood pressure not controlled by medications
  • * Serious angina pectoris or chest pain
  • * Stroke within the past three months
  • * Known allergy to propylene glycol or vegetable glycerin
  • * Serious underlying arrhythmias, irregular heartbeat or abnormal heart rhythm
  • * Live in same household as another study participant

Ages Eligible for Study

21 Years to

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

Yes

Collaborators and Investigators

Ohio State University Comprehensive Cancer Center,

Theodore L Wagener, PhD, PRINCIPAL_INVESTIGATOR, Ohio State University Comprehensive Cancer Center

Study Record Dates

2028-04-12