RECRUITING

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

This protocol studies the clinical outcome of patients with active thyroid disease with visually significant signs and symptoms of proptosis, pain, diplopiam lid/orbital edema, or lid/orbital erythema recommended for treatment with teprotumumab infusion (Tepezza®). Patients recommended for treatment will be evaluated by an oculoplastic surgeon (Dr. Eva Chou) and endocrinologist (Dr. Thanh Hoang).

Official Title

The Effect of Teprotumumab on Thyroid Eye Disease and Thyroid Dysfunction

Quick Facts

Study Start:2021-05-12
Study Completion:2027-12-12
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06275373

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:Yes
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * only DOD beneficiaries
  2. * adult patients 18 years of age or older
  3. * adult patients with proptosis, ocular/orbital pain, diplopia, lid/orbital edema, or lid/orbital erythema associated with autoimmune thyroid disease
  1. * Patients with evidence of compressive optic neuropathy necessitating urgent orbital decompression or external beam radiation
  2. * patients with a history of uncontrolled diabetes mellitus
  3. * patients with a history/diagnosis of uncontrolled inflammatory bowel disease
  4. * patients under age 18 years
  5. * patients who are pregnant or trying to become pregnant.

Contacts and Locations

Study Contact

THANH D HOANG, DO
CONTACT
3012955165
thanh.d.hoang.mil@health.mil
Iris Morris, PhD
CONTACT
3013194599
iris.e.morris3.civ@health.mil

Principal Investigator

Thanh D Hoang, DO
PRINCIPAL_INVESTIGATOR
Walter Reed National Military Medical Center

Study Locations (Sites)

Walter Reed National Military Medical Center
Bethesda, Maryland, 20889
United States

Collaborators and Investigators

Sponsor: Walter Reed National Military Medical Center

  • Thanh D Hoang, DO, PRINCIPAL_INVESTIGATOR, Walter Reed National Military Medical Center

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2021-05-12
Study Completion Date2027-12-12

Study Record Updates

Study Start Date2021-05-12
Study Completion Date2027-12-12

Terms related to this study

Keywords Provided by Researchers

  • Thyroid eye disease
  • Graves ophthalmopathy
  • Graves disease

Additional Relevant MeSH Terms

  • Thyroid Eye Disease
  • Graves Ophthalmopathy
  • Graves Disease