Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test

Description

This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit.

Conditions

Mild Traumatic Brain Injury

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Study Details

Study overview

This study aims to compare symptom provocation, physiologic response, and rate of perceived (RPE) between the Buffalo Concussion Treadmill Test (BCTT) and a Modified Dynamic Exertion (mEXiT) test after sport related concussion in adolescents aged 14-17. Participants will be enrolled at their initial concussion clinical visit within 14 days of their injury, and randomly assigned to either the BCTT or mEXiT group. Participants will complete a single visit.

Comparing Symptom Provocation and Physiological Response Between Buffalo Concussion Treadmill Test (BCTT) Protocol and Modified Dynamic Exertion Test (mEXiT) Post Concussion

Post-Concussion Differences Between Buffalo Concussion Treadmill Test (BCTT) and Modified Dynamic Exertion (mEXiT) Test

Condition
Mild Traumatic Brain Injury
Intervention / Treatment

-

Contacts and Locations

Pittsburgh

UPMC/Univ of Pgh Sports Medicine Concussion Research Program, Pittsburgh, Pennsylvania, United States, 15203

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosed with a sport related concussion within 14 days of injury
  • * Participants referred to exertion therapy after a trained clinician from University of Pittsburgh Medical Center (UPMC) Sports Medicine Concussion Program has interpreted neurocognitive, vestibular, and clinical interview outcomes and determined the participant is capable of completing structured exercise.
  • * Medically cleared from a previous concussion within the past 6 months
  • * More than 2 previous concussions (excluding current injury)
  • * History of brain surgery or traumatic brain injury (TBI) (based on Glasgow Coma Scale of \<13)
  • * History of neurological disorder (seizure disorder, epilepsy, brain tumors or malformations)
  • * Current history of pre-existing vestibular disorder or oculomotor condition
  • * Currently taking antidepressant, anticoagulant, beta-blocker, or anticonvulsant prescription medications
  • * Incapable of treadmill running up to 5.5 miles per hour (mph) and 4.5 mph for males and females respectively (self-reported).
  • * Diagnosed with a cardiac, peripheral, or cerebrovascular disease (type 1 or 2 diabetes, or renal disease.
  • * Experienced chest pain or shortness of breath while at rest or with mild exertion.
  • * Lose balance because of dizziness or have lost consciousness (aside from concussion) from exertion
  • * Currently have (or have had within the past 12 months) a bone, joint, or soft tissue (muscle, ligament, or tendon) problem that could be made worse by physical activity
  • * Been told by a doctor to only conduct physical activity under medical supervision.

Ages Eligible for Study

14 Years to 17 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Pittsburgh,

Anthony P Kontos, PhD, PRINCIPAL_INVESTIGATOR, University of Pittsburgh

Study Record Dates

2025-03-31