Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder

Description

Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1. To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game. 2. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of Interest (ROI) of changes in the Default Mode Network and Cerebellum circuits and their activation levels in those networks. Secondary Outcomes: 1.To observe the impacts and outcome of cerebellar transcranial direct current stimulation (tDCS) measuring the differences between anodal and cathodal stimulation. To observe potential increases in responses to social stimuli, decreases in eating disorder/depressive symptomology via cathodal stimulation. To also observe potential little to no changes in social stimuli and eating disorder/depressive symptomology via anodal stimulation.

Conditions

Anorexia Nervosa

Study Overview

Study Details

Study overview

Hypothesis: Will the use of tDCS brain modulation in the cerebellum assist in restricted behaviors, social cognition and cognitive flexibility in women with anorexia nervosa in addition to other therapies? Primary Outcomes: 1. To observe the impacts and outcomes of cerebellar transcranial direct current stimulation (tDCS) on social behaviors measured by Cyberball and Trust Game. 2. To observe the neuropsychological impacts of cerebellar tDCS through fMRI imaging as well as looking at the Region of Interest (ROI) of changes in the Default Mode Network and Cerebellum circuits and their activation levels in those networks. Secondary Outcomes: 1.To observe the impacts and outcome of cerebellar transcranial direct current stimulation (tDCS) measuring the differences between anodal and cathodal stimulation. To observe potential increases in responses to social stimuli, decreases in eating disorder/depressive symptomology via cathodal stimulation. To also observe potential little to no changes in social stimuli and eating disorder/depressive symptomology via anodal stimulation.

Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder- A Pilot Study

Cerebellar tDCS Stimulation in Children and Adult Women With Anorexia Nervosa Disorder

Condition
Anorexia Nervosa
Intervention / Treatment

-

Contacts and Locations

Dallas

UT Southwestern Multispecialty Psychiatry Clinic, Dallas, Texas, United States, 75247

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Diagnosis of Anorexia Nervosa (AN)
  • * Female participants
  • * Age 15-30 years old inclusive at time of enrollment
  • * Ability of parent or legal guardian to provide informed consent if participant is under 18 years old.
  • * Ability of patients ages 15-17 to give assent to the study.
  • * Completion of the signed HIPAA authorization form by a parent or legal guardian or by participants (18 years of age).
  • * Pregnancy
  • * Known history of traumatic brain injury that required medical care
  • * Non-English speaking (based on standardized neuropsychological testing and questionnaires)
  • * Claustrophobic
  • * Brain Implants
  • * Pacemakers
  • * Hearing or visual impairment
  • * Any biomedical or metal implants in any part of the body (excluding orthopedic implants)

Ages Eligible for Study

15 Years to 30 Years

Sexes Eligible for Study

FEMALE

Accepts Healthy Volunteers

No

Collaborators and Investigators

University of Texas Southwestern Medical Center,

Study Record Dates

2026-01-02