Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

Description

Observational two phase, retrospective and prospective registry study to assess the prevalence of and characterize outcomes of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS) and to better define the underlying pathophysiology of AD following BS.

Conditions

Autonomic Dysfunction, Orthostatic Intolerance

Study Overview

Study Details

Study overview

Observational two phase, retrospective and prospective registry study to assess the prevalence of and characterize outcomes of autonomic dysfunction (AD) in patients who undergo bariatric surgery (BS) and to better define the underlying pathophysiology of AD following BS.

Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

Autonomic Dysfunction in Patients Following Bariatric Surgery: The ADiPOSE Study

Condition
Autonomic Dysfunction
Intervention / Treatment

-

Contacts and Locations

Overland Park

Menorah Medical Center, Overland Park, Kansas, United States, 66209

Overland Park

Bariatric and Metabolic Specialists, Overland Park, Kansas, United States, 66211

Overland Park

Kansas City Heart Rhythm Institute - Roe Clinic, Overland Park, Kansas, United States, 66211

Overland Park

Overland Park Regional Medical Center, Overland Park, Kansas, United States, 66215

Independence

Centerpoint Medical Center Clinic, Independence, Missouri, United States, 64057

Independence

Centerpoint Medical Center, Independence, Missouri, United States, 64057

Kansas City

Research Medical Center Clinic, Kansas City, Missouri, United States, 64032

Kansas City

Research Medical Center, Kansas City, Missouri, United States, 64032

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

For general information about clinical research, read Learn About Studies.

Eligibility Criteria

  • * Between the age of 18 - 85 years
  • * Can provide consent
  • * Negative urine B-hCG
  • * Continued follow-up with the bariatric surgery team.
  • * BS includes one of the following: gastric bypass, sleeve gastrectomy, and biliopancreatic diversion with duodenal switch.
  • * Phase I: Underwent BS within the last 3 years
  • * Phase II: Will undergo BS within the next 3 months or underwent BS in the last 30 days
  • * Unable to provide consent
  • * Pregnant or breastfeeding
  • * BMI \< 35
  • * Revision surgery of one of the following BS from above
  • * Prior history of autonomic dysfunction prior to BS
  • * Developed AD 72 months post-procedure
  • * No evidence of AD/OI

Ages Eligible for Study

18 Years to 85 Years

Sexes Eligible for Study

ALL

Accepts Healthy Volunteers

No

Collaborators and Investigators

Kansas City Heart Rhythm Research Foundation,

Dhanunjaya Lakkireddy, PRINCIPAL_INVESTIGATOR, Kansas City Heart Rhythm Institute

Study Record Dates

2024-12