RECRUITING

Home Tele Rehabilitation Therapy for Vascular Dementia

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Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

To determine whether the home telerehabilitation therapy is feasible and lessens caregiver burden in chronic stroke patients with and without vascular dementia (VaD)

Official Title

Home Tele Rehabilitation Therapy for Vascular Dementia

Quick Facts

Study Start:2024-12-14

Study Completion:2026-04-01

Study Type:Not specified

Phase:Not Applicable

Enrollment:Not specified

Status:RECRUITING

Study ID

NCT06289569

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years to 110 Years

Sexes Eligible for Study:ALL

Accepts Healthy Volunteers:No

Standard Ages:ADULT, OLDER_ADULT

Inclusion Criteria	Exclusion Criteria
* Symptomatic ischemic or hemorrhagic stroke verified by computerized axial tomography or magnetic resonance imaging * at least 6 months post stroke * At least some active movement in the affected upper extremity (MRS 1 or more in shoulder elbow or wrist) * Ability to provide informed consent, or LAR able to provide consent * Expressed willingness to comply with all study procedures and attend all study-related visits for both the patient and at least one caregiver. * Age ≥ 18. * Ability to follow one-step commands. * Community-dwelling with transportation to evaluation sessions. * Ability to operate the therapy system with minimal assistance, including sufficient corrected vision to perceive objects from a distance of 5 feet. * Modified Ashworth Scale Score 3 or less in the involved upper extremity * Passive range of motion within functional ranges at the shoulder, elbow, wrist and hand	* Patients with history of severe alcohol or drug abuse, psychiatric illnesses like severe depression, poor motivational capacity, or severe language disturbances, particularly of receptive nature or with serious cognitive deficits (defined as unable to follow study instructions even with help from caregiver). * Patients with bilateral paresis, or weakness or sensory damage due to peripheral causes (e.g. peripheral nerve injury, muscle or orthopedic injury etc.) * Patients with severe uncontrolled medical problems that would render intensive rehabilitation unfeasible or unsafe (e.g. cardiovascular disease, unstable cardiac arrhythmia, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, or a deteriorated condition due to age, epilepsy or others). * Concurrent participation in other experimental upper extremity rehabilitation trials that would interfere with results. * Non-English-speaking individuals will only be eligible if they can provide the appropriate translator for all the sessions of the study as no funding is available to pay for such services. However, we plan to include them once funding has been secured in the subsequent larger trial. * Pregnancy * Prisoners

Inclusion Criteria

Exclusion Criteria

* Symptomatic ischemic or hemorrhagic stroke verified by computerized axial tomography or magnetic resonance imaging
* at least 6 months post stroke
* At least some active movement in the affected upper extremity (MRS 1 or more in shoulder elbow or wrist)
* Ability to provide informed consent, or LAR able to provide consent
* Expressed willingness to comply with all study procedures and attend all study-related visits for both the patient and at least one caregiver.
* Age ≥ 18.
* Ability to follow one-step commands.
* Community-dwelling with transportation to evaluation sessions.
* Ability to operate the therapy system with minimal assistance, including sufficient corrected vision to perceive objects from a distance of 5 feet.
* Modified Ashworth Scale Score 3 or less in the involved upper extremity
* Passive range of motion within functional ranges at the shoulder, elbow, wrist and hand

* Patients with history of severe alcohol or drug abuse, psychiatric illnesses like severe depression, poor motivational capacity, or severe language disturbances, particularly of receptive nature or with serious cognitive deficits (defined as unable to follow study instructions even with help from caregiver).
* Patients with bilateral paresis, or weakness or sensory damage due to peripheral causes (e.g. peripheral nerve injury, muscle or orthopedic injury etc.)
* Patients with severe uncontrolled medical problems that would render intensive rehabilitation unfeasible or unsafe (e.g. cardiovascular disease, unstable cardiac arrhythmia, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, or a deteriorated condition due to age, epilepsy or others).
* Concurrent participation in other experimental upper extremity rehabilitation trials that would interfere with results.
* Non-English-speaking individuals will only be eligible if they can provide the appropriate translator for all the sessions of the study as no funding is available to pay for such services. However, we plan to include them once funding has been secured in the subsequent larger trial.
* Pregnancy
* Prisoners

Contacts and Locations

Study Contact

Meyyammai Narayanan, MPH

CONTACT

908-227-7275

mknarayanan@houstoethodist.org

Rachel Markley, MPH

CONTACT

(713)-441-3770

rmarkley@houstonmethodist.org

Principal Investigator

Timea Hodics, MD

PRINCIPAL_INVESTIGATOR

The Methodist Hospital Research Institute

Study Locations (Sites)

Houston Methodist Hospital

Houston, Texas, 77030

United States

Collaborators and Investigators

Sponsor: The Methodist Hospital Research Institute

Timea Hodics, MD, PRINCIPAL_INVESTIGATOR, The Methodist Hospital Research Institute

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-12-14

Study Completion Date2026-04-01

Study Record Updates

Study Start Date2024-12-14

Study Completion Date2026-04-01

Terms related to this study

Additional Relevant MeSH Terms

Dementia, Vascular
Stroke Sequelae