A Comparative Clinical Study to Assess Pain Score and Wound Healing Following Fractional Ablation With a DFG Laser and CO2 Laser

Eligibility Criteria

• * Subjects must be able and willing to provide written informed consent and comply with the requirements of the study protocol;
• * Subjects must be in good general health, based on answers provided during the screening visit;
• * Subjects must be able to read and understand English.
• * Subjects must be above the age of 18.
• * Subjects must have no history of skin conditions that affect the integrity of the skin barrier.
• * Are pregnant or lactating;
• * Have a history of drug or alcohol abuse or have reported habitual alcohol intake greater than 2 standard drinks per day \[e.g., 2 beers, 2 glasses of wine, or 2 mixed drinks\];
• * Are smoking or have a history of smoking;
• * Presence of eczema, psoriasis, skin wounds or ulcers, or any other skin disease on the thighs;
• * Have birth marks, tattoos, scars, or any other disfiguration of the skin in the skin area of interest;
• * Presence of sunburn or tan in the treatment area;
• * Use of any topical application of retinoids in the area of interest or systemic retinoids in the past 6 months;
• * Use of any prescription topical medication, such as corticosteroids or hydroquinone on the skin area of interest in the past 6 months;
• * History of blood-clotting abnormality;
• * History of keloid formation or hypertrophic scarring;
• * History of allergic reaction to local anesthesia, aluminum chloride, and/or glycerol;
• * Investigator, interfere with study evaluations or pose a risk to subject safety during the study;
• * Exhibits any clinical conditions or takes any medication which in the opinion of the investigator may interfere with the study or pose a risk to subject safety during the study;
• * Is not able to follow study protocol.