RECRUITING

Massed Prolonged Exposure for PTSD in Substance Use Treatment

Study Overview

This clinical trial focuses on testing the efficacy of different digital interventions to promote re-engagement in cancer-related long-term follow-up care for adolescent and young adult (AYA) survivors of childhood cancer.

Description

The goal of this clinical trial is to learn if receiving Prolonged Exposure Therapy for PTSD in massed format (multiple sessions weekly) is as effective as receiving it with sessions once per week among veterans with PTSD and substance use disorder in intensive outpatient substance use treatment. The main questions it aims to answer are: * Will the massed format help participants complete and benefit from Prolonged Exposure in terms of PTSD symptoms? * Will it help participants reduce substance use? Participants who are in intensive substance use treatment will be asked to complete Prolonged Exposure with either weekly sessions or multiple sessions per week.

Official Title

Clinical Effectiveness and Implementation of Massed Prolonged Exposure for PTSD Among Veterans in Intensive Outpatient Substance Use Treatment (MPE)

Quick Facts

Study Start:2024-09-01
Study Completion:2027-08
Study Type:Not specified
Phase:Not Applicable
Enrollment:Not specified
Status:RECRUITING

Study ID

NCT06296186

Participation Criteria

Researchers look for people who fit a certain description, called eligibility criteria. Some examples of these criteria are a person's general health condition or prior treatments.

Ages Eligible for Study:18 Years
Sexes Eligible for Study:ALL
Accepts Healthy Volunteers:No
Standard Ages:ADULT, OLDER_ADULT
Inclusion CriteriaExclusion Criteria
  1. * Veterans
  2. * age 18+
  3. * who have served since September 2001
  4. * who are enrolled in a SUD IOP at a participating VA
  5. * meet DSM-5 criteria for a current SUD (Tobacco Use Disorder alone not sufficient for inclusion)
  6. * meet DSM-5 criteria for PTSD
  7. * report substance use at least 20 of the last 90 days
  8. * are able to give informed consent.
  1. * severe cognitive impairment
  2. * current suicidal or homicidal intent requiring immediate treatment
  3. * current unstable psychotic or manic symptoms not attributable to SUD

Contacts and Locations

Study Contact

Sonya Norman, PhD
CONTACT
858-518-8266
snorman@ucsd.edu
Kaitlyn Panza, PhD
CONTACT
858-552-8585
kaitlyn.panza@va.gov

Principal Investigator

Shannon Kehle-Forbes, PhD
PRINCIPAL_INVESTIGATOR
University of Minnesota

Study Locations (Sites)

VA San Diego Healthcare System
San Diego, California, 92161
United States
VA Tampa Healthcare System
Tampa, Florida, 33612
United States
VA Atlanta Healthcare System
Atlanta, Georgia, 30033
United States
Hines VA Healthcare System
Chicago, Illinois, 60141
United States

Collaborators and Investigators

Sponsor: Veterans Medical Research Foundation

  • Shannon Kehle-Forbes, PhD, PRINCIPAL_INVESTIGATOR, University of Minnesota

Study Record Dates

These dates track the progress of study record and summary results submissions to ClinicalTrials.gov. Study records and reported results are reviewed by the National Library of Medicine (NLM) to make sure they meet specific quality control standards before being posted on the public website.

Study Registration Dates

Study Start Date2024-09-01
Study Completion Date2027-08

Study Record Updates

Study Start Date2024-09-01
Study Completion Date2027-08

Terms related to this study

Additional Relevant MeSH Terms

  • Stress Disorders, Post-Traumatic
  • Substance Use Disorders